Results 141 to 150 of about 289,299 (297)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Cooling sensation biosensor coupled with the Chou-Talalay method for quantitative assessment of interaction patterns in binary cooling agent mixtures. [PDF]

Curr Res Food Sci
Wan B, Yan Q, Xie F, Hua C, Nie C, Li X, Shang P, Zhang X, Wang H, Peng B, Ma C, Zhao G.   +11 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Postoperative Cutaneous Sensory Recovery After Different Surgical Approaches for Microtia and Ear Reconstruction. [PDF]

Plast Reconstr Surg Glob Open
Willens SH, Alaniz L, Humphrey J, Shah N, Antongiovanni J, Mosieri CA, Jaffurs DC, Vyas RM, Pfaff MJ.   +8 more
europepmc   +1 more source

Grouping and multidimensional organization of respiratory sensations [PDF]

, 1988
Andrew Harver, John C. Balrd, Joan F. McGovern, J. Andrew Daubenspeck   +3 more
openalex   +1 more source

Willingness to experience unpleasant thoughts, emotions, and bodily sensations at admission does not predict treatment outcome in inpatients with obsessive–compulsive disorder

, 2023
Eva Zisler, Adrian Meule, Stefan Koch, Ulrich Voderholzer   +3 more
openalex   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Nerve Grafts in Breast Reconstruction: A Narrative Review. [PDF]

Breast J
Shen Y, Zhang J, Liu Y, Cai H.
europepmc   +1 more source

Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation [PDF]

, 2018
Chun-Chun Cheng, Ko Tsutsui, Toru Taguchi, Noriko Sanzen, Asako Nakagawa, Kisa Kakiguchi, Shigenobu Yonemura, Chiharu Tanegashima, Sean D. Keeley, Hiroshi Kiyonari, Yasuhide Furuta, Yasuko Tomono, Fiona M. Watt, Hironobu Fujiwara   +13 more
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source