Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Sensory Processing in People Experiencing Homelessness in Spain: A Pilot Study. [PDF]
Cal-Herrera A +6 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Minimal Impact of Sensation-Related Items on the Association Between Alexithymia and Self-Report Measures of Interoception. [PDF]
Ottley-Porter A +3 more
europepmc +1 more source
The Mediating and Moderating Role of Sensation-Seeking in the Association between Resting Heart Rate and Antisocial Behavior [PDF]
Sofi Oskarsson +2 more
openalex +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Evaluation of Over-the-Counter Cutaneous Lidocaine Cream for Temporary Deafferentation in Upper Limb Rehabilitation: A Cross-Sectional Study. [PDF]
Baker K +9 more
europepmc +1 more source
Radiation Effects of Sensation on Contact with Materials
Hironobu Kajii
openalex +1 more source
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
The association between interoception and psychopathic traits. [PDF]
Gao Y, Murphy A, Kofler L.
europepmc +1 more source

