Results 191 to 200 of about 289,299 (297)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Reading about sensations recruits the posterior insula: An intracranial EEG study. [PDF]

iScience
Dupont W, Dornier V, Palluel-Germain R, Robin A, Lachaux JP, Kahane P, Minotti L, Vidal JR, Perrone-Bertolotti M.   +8 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Verifying the physiological significance of the preference for low facial temperature in humans. [PDF]

Curr Res Physiol
Matsuda-Nakamura M, Wada S, Nagashima K.
europepmc   +1 more source

Sensation of a lump in the throat elicited by atropine sulfate injection.

, 1987
Mikikazu Yamagiwa, Masahiko Kubo, Teruhiko Harada, Yasuo Sakakura   +3 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Future Time Perspective and Locomotion Jointly Predict Anticipatory Pleasure in Adolescence: An Integrative Hierarchical Model. [PDF]

Eur J Investig Health Psychol Educ
Mancone S, Zanon A, Gentile A, Marotta G, Di Siena F, Falese L, Diotaiuti P.   +6 more
europepmc   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Electronic Gastroscopy in Identifying Hidden Tonsillar Foreign Bodies: A Case of a Completely Embedded Sunflower Seed Shell. [PDF]

Am J Case Rep
Liang D.
europepmc   +1 more source

Table 1_Emotional responses to auditory hierarchical structures is shaped by bodily sensations and listeners’ sensory traits.docx

Maiko Minatoya (21675962), Tatsuya Daikoku (5194316), Yasuo Kuniyoshi (438060)   +2 more
openalex   +1 more source