Results 31 to 40 of about 107,496 (247)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Burning mouth syndrome: A review on its diagnostic and therapeutic approach

Journal of Pharmacy and Bioallied Sciences, 2014
Burning mouth syndrome (BMS), a chronic and intractable orofacial pain syndrome is characterized by the presence of burning sensation of the oral mucosa in the absence of specific oral lesion.
R Aravindhan, Santhanam Vidyalakshmi, Muniapillai Siva Kumar, C Satheesh, A Murali Balasubramanium, V Srinivas Prasad   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Effects of parental mental health and family environment on impulsivity in preadolescents: a longitudinal ABCD study®

Frontiers in Behavioral Neuroscience, 2023
IntroductionImpulsivity is a known risk factor for the development of substance use disorders and other psychiatric conditions that is influenced by both genetics and environment.
Nioud Mulugeta Gebru, Nioud Mulugeta Gebru, Priscila Dib Goncalves, Rick A. Cruz, Wesley K. Thompson, Nicholas Allegair, Alexandra Potter, Hugh Garavan, Julie Dumas, Robert F. Leeman, Robert F. Leeman, Micah Johnson   +11 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Genetic analyses of the bidirectional associations between common mental disorders and asthma

Frontiers in Psychiatry
ObjectiveAlthough extensive research has explored the link between mental disorders and asthma, the characteristics and patterns of this association are still unclear.
Zian Yan, Zian Yan, Jingjing Chen, Lijun Guo, Hongwei Zhang, Yanqiu Ding, Yanqiu Ding, Gaocan Ren, Yiyi Mao, Ruina Bai, Xiaochang Ma   +10 more
doaj   +1 more source

Taste disorders: A review

Journal of Indian Academy of Oral Medicine and Radiology, 2014
For maintenance of the health of an individual, taste sensation is very important. It is an important sensation that serves to assess the nutritious content of food, support oral intake, and prevent ingestion of potentially toxic substances. Disturbances
Vijay Kumar Ambaldhage, Jaishankar Homberhalli Puttabuddi, Purnachandrarao Naik Nunsavath, Yehoshuva R Tummuru   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Clinical Features of Idiopathic Paroxysmal Kinesigenic Dyskinesia

Pediatric Neurology Briefs, 2004
The clinical features of 121 patients, referred for genetic study, with a presumptive diagnosis of idiopathic paroxysmal kinesigenic dyskinesia (PKD), were reviewed by a multicenter panel and reported from the University of Calfornia, San Francisco.
J Gordon Millichap
doaj   +1 more source