Results 51 to 60 of about 205,233 (304)
Social Determinants of Health, 2016 Background and objective: The purpose of this research is to study the relation between emotional intelligence, sensation seeking and marital satisfaction among female teachers in the city of Borujerd.Materials and Methods: The statistical population is ...
Hatam Siavoshi +3 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
, 2013 Many personality traits are popular sources of research for a short time, and then, like the constructs on which they are based, they gradually fade away. In contrast, Sensation Seeking (otherwise known as Novelty Seeking, Arousal Seeking, Excitement Seeking, and other “seeking” labels) has had a steady increase in citations over the half century since
Joseph Glicksohn, Marvin Zuckerman
openaire +2 more sources
Consumer innovative behavior in vacation travel [PDF]
, 2011 This paper focuses on the study of innovative behavior of tourists through the dimensions of sensation seeking. To our knowledge, few studies have explored the dimensions of sensation seeking in relation to the innovative behavior of tourists in their ...
López-Bonilla, Jesús Manuel +2 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Sensation seeking and impulsivity as predictors of aggression in adolescents [PDF]
Psychology, Society & Education, 2016 Adolescence is a stage in which impulsivity and sensation seeking are presented as two factors that come together with a wide range of changes inherent to adolescent development.
José J. GÁZQUEZ +3 more
doaj
Online and live regular poker players: Do they differ in impulsive sensation seeking and gambling practice? [PDF]
, 2016 Background and aims Online gambling appears to have special features, such as anonymity, speed of play and permanent availability, which may contribute to the facilitation and increase in gambling practice, potentially leading to problem gambling.
Barrault, Servane, Varescon, Isabelle
core +5 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source