Results 51 to 60 of about 205,480 (327)

Sensation seeking and impulsivity as predictors of aggression in adolescents [PDF]

open access: yesPsychology, Society & Education, 2016
Adolescence is a stage in which impulsivity and sensation seeking are presented as two factors that come together with a wide range of changes inherent to adolescent development.
José J. GÁZQUEZ   +3 more
doaj  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Online and live regular poker players: Do they differ in impulsive sensation seeking and gambling practice? [PDF]

open access: yes, 2016
Background and aims Online gambling appears to have special features, such as anonymity, speed of play and permanent availability, which may contribute to the facilitation and increase in gambling practice, potentially leading to problem gambling.
Barrault, Servane, Varescon, Isabelle
core   +4 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Role of Sensation Seeking in Sensitivity to d-amphetamine Reinforcement [PDF]

open access: yes, 2014
Psychomotor stimulant abuse is a significant public health problem. While many individuals experiment with stimulants, there is marked variability in individuals\u27 behavioral and subjective response to these drugs and these differences may be ...
Patrick, Mollie E.
core   +1 more source

Potential benefits of an adaptive forward collision warning system [PDF]

open access: yes, 2008
Forward collision warning (FCW) systems can reduce rear-end vehicle collisions. However, if the presentation of warnings is perceived as mistimed, trust in the system is diminished and drivers become less likely to respond appropriately.
A. Hamish Jamson   +17 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Sensation-Seeking

open access: yes, 2013
Many personality traits are popular sources of research for a short time, and then, like the constructs on which they are based, they gradually fade away. In contrast, Sensation Seeking (otherwise known as Novelty Seeking, Arousal Seeking, Excitement Seeking, and other “seeking” labels) has had a steady increase in citations over the half century since
Joseph Glicksohn, Marvin Zuckerman
openaire   +2 more sources

A Study of the Relationship between Sensation Seeking and Marital Satisfaction

open access: yesروانشناسی بالینی و شخصیت, 2005
The purpose of the present study was to investigate the relationship between sensation seeking and: marital satisfaction, gender, education, marital duration and age differences of the couples.
M.B. Kajbaf, H. Neshatdust, Gh. Khaloei
doaj  

Home - About - Disclaimer - Privacy