Results 111 to 120 of about 8,451,938 (279)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Prejudice and Presupposition in Offensive Language

open access: yesNordicum-Mediterraneum, 2017
In this paper I give a short introduction to the standard way to treat offensive language in contemporary philosophy of language, without giving details on the very rich contemporary literature on the problem.
Carlo Penco
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The pragmatics of artistic discourse and speech genres

open access: yesOpera slavica, 2015
The paper deals with the problem of communication depended on the speech and cognitive strategy of the type of discourse, in the framework of which the relevant communication is done.
Nikolaj Fiodorovič Alefirenko   +1 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Subtext Meanings as Components of Prosaic Text Sense Structure

open access: yesOriental Studies, 2018
The subtext as a linguistic phenomenon appearing as a result of some syntactic constructions usage is described in the article. Depending on the used linguistic means and on appearing semantics the subtext is divided into two types: emotional and ...
Natalia Pushkareva
doaj  

ARCHITECTONICS OF SPACE OF HUMAN BEINGIN THE PHILOSOPHY OF N. N. TRUBNIKOV [PDF]

open access: yesВестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия, 2011
This article represents the conception of soviet philosopher Nikolay Trubnikov about space in connection with a category of sense or purpose of human being.
E. GLINCHIKOVA
doaj  

AutoSense Model for Word Sense Induction

open access: yes, 2018
Word sense induction (WSI), or the task of automatically discovering multiple senses or meanings of a word, has three main challenges: domain adaptability, novel sense detection, and sense granularity flexibility. While current latent variable models are
Amplayo, Reinald Kim   +2 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

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