Results 141 to 150 of about 2,504,261 (316)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Integrating Cyc and Wikipedia: folksonomy meets rigorously defined common-sense
, 2008 Integration of ontologies begins with establishing mappings between their concept entries. We map categories from the largest manually-built ontology, Cyc, onto Wikipedia articles describing corresponding concepts.
O Medelyan (13648762) +1 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Sometimes less is more : Romanian word sense disambiguation revisited
, 2007 Recent approaches to Word Sense Disambiguation (WSD) generally fall into two classes: (1) information-intensive approaches and (2) information-poor approaches.
Kübler, Sandra, Dinu, Georgiana
core
DiagnosticsAccurate assessment of vitreous inflammation is essential for the diagnosis, monitoring and management of uveitis. Traditionally, vitritis has been evaluated using subjective clinical grading systems based on vitreous haze and cellular infiltration ...
Maria Carmela Saturno +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2019 The Sense of Place has been addressed in tourism studies as an object of concern to academics and policymakers. From mass tourism to personalized travel, understand the relationship between tourists and places it’s an effort to improve the tourism ...
Cardoso, Antonio, D'Orey, Frederico
core
Capturing lexical variation in MT evaluation using automatically built sense-cluster inventories [PDF]
, 2009 The strict character of most of the existing Machine Translation (MT) evaluation metrics does not permit them to capture lexical variation in translation.
He, Yifan +2 more
core
Discover Artificial IntelligencePlant disease significantly impacts the agricultural economy. It also affects the morphology and colour of leaves, which serve as key markers for diagnosis. Manual classification of disease requires trained professionals; it is tedious and time consuming.
Vijay R. N. Prabhakar +4 more
doaj +1 more source