Results 41 to 50 of about 1,781 (212)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The sense of coherence scale and relationships between sense of coherence, sociodemographic variables and chronic disease

Scientific Reports
Sense of coherence (SOC) is a global orientation that represents a core concept of the salutogenic model of health. No Polish version of the SOC questionnaire currently exists that has been validated on a representative sample.
Arkadiusz M. Jasiński, Romuald Derbis, Jarosław Rakoczy, Magdalena Wrzesińska   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Latent profile analysis of sense of coherence and relationship with meaning of life and professional identity among nursing undergraduate

BMC Nursing
Background Enhancing nursing undergraduates’ sense of coherence is crucial for the growth of the nursing workforce. Yet, existing research primarily examines the aggregate level of sense of coherence among nursing undergraduates and its correlations with
Yating Liu, Dudu Zhang, Song Ge, Shanshan Wang, Xin Li, Zhenxiang Zhang, Beilei Lin, Suyan Chen, Yongxia Mei   +8 more
doaj   +1 more source

A longitudinal examination of the effect of physical exercise on the emotional states of college students: exploring the sense of coherence as a mediator through a cross-lagged panel analysis

Frontiers in Behavioral Neuroscience
PurposeThis longitudinal study aimed to investigate the causal relationship between physical exercise and emotional states among university students, focusing on the mediating role of sense of coherence.MethodA total of 1,215 university students (aged 18–
Yunxia Cao, Yunxia Cao, Lin Luo
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Relationship between sense of coherence and professional identity in nursing students: the chain mediating effect of academic emotion and self-esteem

BMC Nursing
Background The psychological conditions of nursing students are quite important, and professional identity is an important part of the stable development of the nursing profession.
Huan Liu, Jin Li, Xiujuan Feng, Rui Liang, Yanan Qi, Jing Zhang   +5 more
doaj   +1 more source

Sense of coherence and the style of interpersonal functioning and coping in adolescence

Health Psychology Report, 2015
Background Sense of coherence is widely discussed with respect to adults. The objective of this study was to find experiences (interpersonal relations and coping) forming the sense of coherence in the adolescent period.
Agnieszka Kulik
doaj   +1 more source

Salutogenesis: Sense of Coherence in Adolescence [PDF]

, 2016
The main aim of this chapter is to summarize the main finding regarding SOC and adolescents in the last decade since adolescence is a period of growth and development which can potentially influence the emotional, motivational and behavioral components of SOC.
Orna Braun-Lewensohn, Orly Idan, Bengt Lindström, Malka Margalit   +3 more
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source