Results 71 to 80 of about 1,542,074 (344)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Distributive principles of economic justice: an Islamic perspective

open access: yesIndonesian Journal of Islam and Muslim Societies, 2012
Poverty and impoverishment in the world currently continue to increase as aresult of distributive justice systems and its principles that became the basis ofcontemporary economics did not succeed in allocating and distributing resourcesjustly.
Zakiyuddin Baidhawy
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Keep Tinkering: The Optimist and the Death Penalty [PDF]

open access: yes, 2017
When it comes to capital punishment, it may make sense to be a little bit defeatist. Like abortion, the death penalty is a topic about which you have to presume that you are never going to change anyone else’s mind. Whether the other person views it as a
Rozelle, Susan D.
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Election '08: A Pro-Civil Justice Presidential Platform [PDF]

open access: yes, 2008
Many Presidential candidates claim they stand "for the little guy," but do they have a proactive policy for strengthening our civil justice system so that it works for those whom it was meant to protect? Well, we have some ideas. The Drum Major Institute'
Kia Franklin
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

FEATURES OF THE SENSE OF JUSTICE IN THE YOUTH OF DAGESTAN

open access: yesВестник Кемеровского государственного университета, 2015
Article retractedThe paper presents the features of formation of the sense of justice and legal culture in Dagestan youth. On the basis of sociological poll the author identified the role of the regional factors that have positive influence on the ...
N. A. Asvarov
doaj  

Understanding the Nature and Effects of Police-Citizen Encounters in Social Context: The Road Less Traveled [PDF]

open access: yes, 2013
Aggressive policing tactics have been identified as contributors to declining crime rate trends in urban, culturally diverse neighborhoods. They encompass stop and frisk practices which have spawned negative public opinion that contrasts with its ...
D\u27, Anca Alfred, R.
core   +1 more source

The potential determinants of young people's sense of justice: an international study

open access: yes, 2011
This paper uses reports from 13,000 Grade Nine pupils in five countries to examine issues such as whether they were treated fairly at school, trust their teachers and adults in wider society, are willing to sacrifice teacher attention to help others, and
S. Gorard
semanticscholar   +1 more source

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