Results 101 to 110 of about 108,534 (253)
MMOG players' sense of place in virtual worlds
, 2021 This project explores how game players develop sense of place, the perception that a space has meaning (Bott, 2000; Hummon, 1992) as they interact with the virtual spaces of massively multiplayer online games (MMOGs).
Alvarez, Katrina Paola Banas
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Go Green for the Home Team: Sense of Place and Environmental Sustainability in Sport
, 2016 The sport industry has a tremendous impact on the natural environment. As a result, sport organizations have implemented ways to reduce their impact ranging from energy upgrades, waste management programs, and fan engagement.
McCullough, Brian, Kellison, Timothy
core
, 2023 Fishing communities in many places around the world are facing significant challenges\r\ndue to new policies and environmental developments. While it is imperative to ensure sustainability\r\nof natural resources, many policies may overlook the ...
Griffith, David +2 more
core
Globalisation par le bas ou par le haut ?
Géographie et Cultures, 2009 Commercial streets in multiethnic neighbourhoods are at the crossroads of two currents of globalization, cultural and economic. On the one hand, their range of shops and services and social milieu are shaped by increasing and diversifying flows of ...
Martha Radice
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
International Journal of Ageing and Later Life, 2012 The discussion within gerontology of the relationship between older people and their environment (place attachment and ageing in place in particular) has been based on an assumption of familiarity with place.
Judith Phillips +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source