Results 111 to 120 of about 108,534 (253)
Linking activity and place attachment dimensions in enhancing the sense of place [PDF]
, 2007 Sense of place definition includes the point where the physical form, activity and meaning are intertwined in the people experience of a place. In urban design and place quality research, much has been discussed on the influence of the physical form ...
Ujang, Norsidah, Dola, Kamariah
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 1989 Young walkers passing Forestry Commission signs for Grizedale and the Silurian Way. VO of George Isles, Recreation Ranger. Isles talking to the children about the forest and sending them off blindfolded in order to accustom them to using other senses.
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Instagram use and local community experience: paths towards Sense of Place and Sense of Community
, 2021 In modern local communities, individuals get conflicting representations about social meanings, which seem available yet not attainable due to community social and environmental features.
Flora Gatti, Fortuna Procentese
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Ordinary spaces and sense of place
, 2010 Commercial spaces have always represented meaningful places for consumers. From ancient times they have stimulated the call of the exotic, the magical, discovery and entertainment (Goss 1993; McGrath 1998; Maclaran and Stevens 1998).
BORGHINI, STEFANIA +2 more
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Discovering a ‘post-revolutionary’ sense of place in China’s small commodity city of Yiwu [PDF]
The ‘small commodity city’ of Yiwu in China specialises in low-end products, enjoying economic success due to its early establishment of private enterprise, yet relying upon traditional forms of solidarity as well as those provided by the structures of ...
Hulme, Alison
core +1 more source