Results 91 to 100 of about 1,194,157 (299)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of nanoporous membranes thickness in electrochemical biosensing performance: application for the detection of a wound infection biomarker

Frontiers in Bioengineering and Biotechnology
Introduction: Nanoporous alumina membranes present a honeycomb-like structure characterized by two main parameters involved in their performance in electrochemical immunosening: pore diameter and pore thickness.
C. Toyos-Rodríguez, C. Toyos-Rodríguez, D. Valero-Calvo, D. Valero-Calvo, A. Iglesias-Mayor, A. Iglesias-Mayor, A. de la Escosura-Muñiz, A. de la Escosura-Muñiz   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition [PDF]

, 2019
Paul S. Kwon, Shaokang Ren, Seok‐Joon Kwon, Megan E. Kizer, Lili Kuo, Feng Zhou, Fuming Zhang, Domyoung Kim, Keith Fraser, Laura D. Kramer, Nadrian C. Seeman, Jonathan S. Dordick, Robert J. Linhardt, Jie Chao, Xing Wang   +14 more
openalex   +1 more source

Robust Electromagnetic Interference (EMI) Elimination via Simultaneous Sensing and Deep Learning Prediction for RF Shielding-free MRI [PDF]

, 2022
Yujiao Zhao, Linfang Xiao, Vick Lau, Yilong Liu, Alex T. L. Leong, EX Wu   +5 more
openalex   +1 more source

Export of miRNAs from activated macrophages is cooperative and HuR‐dependent

FEBS Letters, EarlyView.
This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Volatile Short-chain Aliphatic Aldehydes Act as Taste Modulators through the Orally Expressed Calcium-sensing Receptor CaSR

, 2023
Seiji Kitajima, Yutaka Maruyama, Motonaka Kuroda   +2 more
openalex   +2 more sources

Sensing microscopic noise events by frequent quantum measurements [PDF]

, 2022
Salvatore Virzì, Laura T. Knoll, Alessio Avella, Fabrizio Piacentini, Stefano Gherardini, Marco Gramegna, Gershon Kurizki, Abraham G. Kofman, Ivo Pietro Degiovanni, Marco Genovese, Filippo Caruso   +10 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source