Results 171 to 180 of about 1,194,157 (299)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

A Methodological Framework for High-Resolution Surface Urban Heat Island Mapping: Integration of UAS Remote Sensing, GIS, and Local Climate Zoning Concept

Stelian Dimitrov, Martin Iliev, Bilyana Borisova, Lidiya Semerdzhieva, Stefan Petrov   +4 more
openalex   +2 more sources

Effect of Portable Ground Control Points on the Accuracy of UAV-Based Remote Sensing Data for Plant Health Prediction

, 2021
Subodh Bhandari
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Synthesis and microstructural properties of Pt-decorated α-Fe₂O₃ nanotubes for hydrogen gas sensing applications. [PDF]

RSC Adv
Šoltić M, Gracheva M, Baran N, Dražić G, Peter R, Lázár K, Štefanić G, Marciuš M, Novosel N, Kiss LF, van Spronsen MA, Ivanda M, Klencsár Z, Gotić M.   +13 more
europepmc   +1 more source

Multisensory Museums, Hybrid Realities, Narration and Technological Innovation: A Discussion Around New Perspectives in Experience Design and Sense of Authenticity

Eva Pietroni
openalex   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A Redundant-Sensing-Based Six-Axis Force/Torque Sensor Enabling Compactness and High Sensitivity. [PDF]

Sensors (Basel)
Lee SY, Sim JY, Seok DY, Kim YB, Shim J, Kim U, Choi HR.   +6 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A synergistic dual-mode biosensor for methotrexate detection leveraging FRET and Ag NP-based UV absorption. [PDF]

RSC Adv
Zhang Q, Teng Q, Duan H, Peng C, Sheng W, Wang W, Li B.   +6 more
europepmc   +1 more source