Results 211 to 220 of about 664,317 (268)

ILA-CSMA: Hybrid Sensing and Adaptive Fair Backoff for Large-Scale LoRa Networks. [PDF]

Sensors (Basel)
Cheng W, Cui H, Yu H.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Molecular mechanisms and applications of antimicrobial secondary metabolites of <i>Bacillus subtilis</i> based on biofilm and quorum sensing. [PDF]

Appl Environ Microbiol
Feng J, Luo H, Zhang Z, Wang Z, Wang M.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Interdigitated capacitive strain sensor enables precise yoga-inspired motion tracking. [PDF]

NPJ Biosens
Papaefstathiou M, Elgendi M, Menon C.
europepmc   +1 more source

Isoreticular Tuning of Conductive Metal-Organic Framework Nanocrystals for the Rapid Detection and Differentiation of Toxic Gases. [PDF]

ACS Nano
Shehayeb EO, Chan JYM, Pennington DL, Hendon CH, Mirica KA.   +4 more
europepmc   +1 more source

Flexible Tactile Sensor System Based on Piezoresistive Layer: Technology and Construction. [PDF]

Sensors (Basel)
Novák V, Volf J, Hrmo R, Kvasnová P, Ryženko V, Novák D, Očkajová A.   +6 more
europepmc   +1 more source

Advanced Pathways for the Preparation of Sensitive Lead(II) Ion Sensor: Ion-Imprinted versus Acid-Assisted Polymerization of 3‑Thiopheneacetic Acid with 1‑Vinylimidazole Monomers. [PDF]

ACS Omega
Kusumkar VV, Svoboda J, Šeděnková I, Hromadková J, Galamboš M, Tomšík E.   +5 more
europepmc   +1 more source

Low-Temperature Ethanol Gas Sensor Based on MoO₃/Nb₂C MXene Composite via Crystal Engineering and Facet Release. [PDF]

Sensors (Basel)
Zhang B, Zhou H, Zhu X, Chen H, Yang Y.
europepmc   +1 more source