Results 121 to 130 of about 814,534 (292)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Recent Progress in Flexible Wearable Sensors Utilizing Conductive Hydrogels for Sports Applications: Characteristics, Mechanisms, and Modification Strategies

Gels
Conductive hydrogels demonstrate substantial potential for flexible wearable sensors in motion monitoring, owing to their unique physicochemical properties; however, current implementations still confront persistent challenges in long-term stability ...
Jie Wu, Jingya Hong, Xing Gao, Yutong Wang, Wenyan Wang, Hongchao Zhang, Jaeyoung Park, Weiquan Shi, Wei Guo   +8 more
doaj   +1 more source

Sensing Mechanism and Excited-State Dynamics of a Widely Used Intracellular Fluorescent pH Probe: pHrodo. [PDF]

J Phys Chem Lett, 2023
Jiang S, He Y, Brandt JH, Zhao L, Chen J.   +4 more
europepmc   +1 more source

Function-led design of multifunctional stimuli-responsive superhydrophobic surface based on hierarchical graphene-titania nanocoating

, 2017
Multifunctional smart superhydrophobic surface with full-spectrum tunable wettability control is fabricated through the self-assembly of the graphene and titania nanofilm double-layer coating.
Liu, Yang
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

SnO₂ Nanowire/MoS₂ Nanosheet Composite Gas Sensor in Self-Heating Mode for Selective and ppb-Level Detection of NO₂ Gas

Chemosensors
The development of low-cost and low-power gas sensors for reliable NO2 gas detection is important due to the highly toxic nature of NO2 gas. Herein, initially, SnO2 nanowires (NWs) were synthesized through a simple vapor–liquid–solid growth mechanism ...
Jin-Young Kim, Ali Mirzaei, Jae-Hun Kim
doaj   +1 more source

Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism. [PDF]

Proc Natl Acad Sci U S A, 2023
Brunello E, Marcucci L, Irving M, Fusi L.   +3 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Acute oxygen-sensing mechanisms. [PDF]

The New England journal of medicine, 2006
Holger K, Eltzschig, Jorn, Karhausen, Volkhard A J, Kempf   +2 more
  +8 more sources