Results 131 to 140 of about 3,945,385 (300)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

SnO₂ Nanowire/MoS₂ Nanosheet Composite Gas Sensor in Self-Heating Mode for Selective and ppb-Level Detection of NO₂ Gas

Chemosensors
The development of low-cost and low-power gas sensors for reliable NO2 gas detection is important due to the highly toxic nature of NO2 gas. Herein, initially, SnO2 nanowires (NWs) were synthesized through a simple vapor–liquid–solid growth mechanism ...
Jin-Young Kim, Ali Mirzaei, Jae-Hun Kim
doaj   +1 more source

Sensing Mechanism and Excited-State Dynamics of a Widely Used Intracellular Fluorescent pH Probe: pHrodo. [PDF]

J Phys Chem Lett, 2023
Jiang S, He Y, Brandt JH, Zhao L, Chen J.   +4 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Border-Enhanced Triple Attention Mechanism for High-Resolution Remote Sensing Images and Application to Land Cover Classification

With the continuous development and popularization of remote sensing technology, remote sensing images have been widely used in the field of land cover classification. Since remote sensing images have complex spatial structure and texture features, it is
Jiahao Chen, Peng Wu, Guoying Wang, Xiaomei Yi, Lufeng Mo   +4 more
core   +1 more source

Gas sensing performance of Ti3C2Tx MXene heterojunction structures in greenhouse environments: a mini review

Frontiers in Chemistry
With the continuous advancement of smart greenhouse technologies, digital and information-based environmental monitoring has emerged as a focal point of research. The development of high-performance gas sensors is central to achieving this objective.
Haoming Zhang, Hongyu Xu, Wen Zeng, Zhongchang Wang, Qu Zhou   +4 more
doaj   +1 more source

Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism. [PDF]

Proc Natl Acad Sci U S A, 2023
Brunello E, Marcucci L, Irving M, Fusi L.   +3 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source