Results 251 to 260 of about 3,965,120 (318)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Development of micro dual temperature-heat flux sensing probe using Pt Thin film for transient heat measurements up to 1400 °C. [PDF]

Microsyst Nanoeng
Wang H, Kong M, Wang H, Zhang F, Yang Z, Hao T, Yang J, Xu R, Zhan Y, Liang J, Liu Z.   +10 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Interaction between Paracetamol Glucuronide and a Glucose-Sensitive Insulin Molecule (NNC2215): Increased Risk of Hypoglycemia. [PDF]

ACS Pharmacol Transl Sci
Sturis J, Alifrangis L, Nielsen PK, Lykke L, Björkbom A, Hvidt M, Brand CL, Kruse T, Johansson E, Granata D, Petersen BO, Rodríguez D, Madsen AR, Halskov KS, Hansen A, Koščová S, Kotek V, Tarus V, Fels JJ, Niclasen AV, Chapman A, Sauerberg P, Slaaby R.   +22 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Real-World Data of Second-Line Amrubicin Monotherapy in Patients With Extensive-Stage Small Cell Lung Cancer Who Received First-Line Chemoimmunotherapy or Chemotherapy: A Multicenter Retrospective Study. [PDF]

Cancer Med
Sonehara K, Tsutsui T, Nozawa S, Agatsuma T, Yamamoto M, Matsuo A, Nakanishi M, Chiaki T, Kato A, Miyahara T, Hachiya T, Kanda S, Hirabayashi T, Yanagisawa K, Araki T, Tateishi K, Hanaoka M.   +16 more
europepmc   +1 more source

Identification of QTLs and genes regulating panicle number through genome-wide association studies in <i>Oryza sativa</i> L. [PDF]

Front Plant Sci
Li F, Ma X, Xie J, Zhu X, Wang X, Liang J, Rashid MAR, Guo H, Zhang Z, Li J, Li Z, Luo J, Zhang H.   +12 more
europepmc   +1 more source

Modulation of BK-like potassium currents by ketamine in rat cochlear outer hair cells. [PDF]

Mol Brain
Yang X, Lu Y, Zhang X, Xu Y, Lin J, Ji F, Zhao Q.   +6 more
europepmc   +1 more source

Timely nudges promote patient portal enrollment and sustained engagement: a randomized controlled trial. [PDF]

JAMIA Open
Brietzke SC, Shermohammed M, Goren A, Rosenbaum GM, Meyer MN, Chabris CF.   +5 more
europepmc   +1 more source