Results 91 to 100 of about 2,243,062 (248)

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Attribute-Based Equality Test over Encrypted Data without Random Oracles

open access: yes, 2020
© 2013 IEEE. Sensitive data would be encrypted before uploading to the cloud due to the privacy issue. However, how to compare the encrypted data efficiently becomes a problem. Public Key Encryption with Equality Test (PKEET) provides an efficient way to
Jianye Huang (17869001)   +5 more
core  

Authorisation using Attribute from Multiple Authorities - A Study of Requirements [PDF]

open access: yes, 2007
This paper presents the results of a survey of requirements for attribute aggregation in authorisation systems, gathered from an international community of security professionals. It then analyses these requirements against 4 generic models for attribute
Klingenstein, Nate   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Silver: an Attribute Grammar System

open access: yes, 2017
Silver is an attribute grammar system which supports higher-order, reference, and collection attributes. It also supports forwarding and provides a modular well-definedness analysis to ensure composability of language extensions.
Michaelson, Dawn   +3 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Sensitive Data Toolkit for Researchers Part 1: Glossary of Terms for Sensitive Data used for Research Purposes

open access: yes, 2020
The Sensitive Data Expert Group of the Portage Network has create a suite of tools for Canadian researchers. These tools have been created to help researchers understand how research data is involved in the research ethics process, and to address the ...
Sensitive Data Expert Group
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Attribute based sanitizable signature scheme

open access: yesTongxin xuebao, 2013
Sensitive information in the document needs to be hidden in cloud computing environment, and attribute based sanitizable signature (ABSS) scheme was proposed to solve this problem. The ABSS scheme brings the character of sanitiz-able into ABS in order to
Xi-meng LIU   +4 more
doaj   +2 more sources

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