Results 181 to 190 of about 10,391,048 (325)

Timing of Prenatal Stress Exposure Predicts Infant Sympathetic Nervous System and Affective Responses. [PDF]

Dev Psychobiol
Martinez-Torteya C, Nuttall AK, Bogat GA, Lonstein JS, Muzik M, Grimm KJ, Granger DA, Levendosky AA.   +7 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Accumulation and sensitive period effects for childhood abuse and financial hardship on depressive symptoms in late adolescence. [PDF]

J Mood Anxiety Disord
Dunn EC, Cheng TW, Zhu Y, Lussier AA, Thompson KN, Smith ADAC, Tiemeier H, Susser ES.   +7 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Susceptible window identification of the relationship between maternal ozone exposure and preterm birth. [PDF]

Int Health
Zhong KK, Yang R, Liu XC, He J, Wen CT, Zhu ZW, Fan MX, Bao T, Zhong Q.   +8 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Ecological Roles of Lichens as Monitors of a Changing Global Environment. [PDF]

Biology (Basel)
Beng Fung MB, Paukov AG, Yuan JW, Wang HX, Cui BY, Liu HJ, Ren Q.   +6 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Performance-enhancing drug use in sports: a Bayesian variable selection and profile regression approach to identifying risk factors and estimating prevalence. [PDF]

Subst Abuse Treat Prev Policy
Vakhitova Z, Mezzetti C, Alston-Knox C, Jowett S, Rhind D, Lin CY, Huang PC, Vergani M, O'Brien K.   +8 more
europepmc   +1 more source

Address assignment sensitive variable partitioning and scheduling for DSPS with multiple memory banks

IEEE International Conference on Acoustics, Speech, and Signal Processing, 2008
C. Xue, Tiantian Liu, Z. Shao, J. Hu, Zhiping Jia, W. Jia, E. Sha   +6 more
semanticscholar   +1 more source