Results 211 to 220 of about 10,108,798 (388)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Science, 2016
N. Mcgranahan, A. Furness, R. Rosenthal, S. Ramskov, R. Lyngaa, S. Saini, M. Jamal-Hanjani, G. Wilson, Nicolai J. Birkbak, C. Hiley, T. Watkins, S. Shafi, N. Murugaesu, R. Mitter, A. Akarca, J. Linares, T. Marafioti, J. Henry, E. V. Van Allen, Diana Miao, B. Schilling, D. Schadendorf, L. Garraway, V. Makarov, N. Rizvi, A. Snyder, M. Hellmann, T. Merghoub, J. Wolchok, S. Shukla, Catherine J. Wu, K. Peggs, T. Chan, S. Hadrup, S. Quezada, C. Swanton   +35 more
semanticscholar   +1 more source

Stability, sensitivity and sensitivity of characterizations [PDF]

Banach Center Publications, 1980
Andrzej S. Kozek, Bogusława Bednarek-Kozek   +1 more
openaire   +2 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Adaptations of the Vertebrate Retina to Low-Light Conditions: A Review. [PDF]

Anat Histol Embryol
Cobo R, Navarro-Sempere A, Segovia Y, García M.   +3 more
europepmc   +1 more source

Sensitivity of Four Species of Bacteroides to Antibiotics [PDF]

, 1955
L. P. Garrod
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Effect of focused ultrasound neuromodulation of the superior mesenteric plexus on insulin sensitivity and post-operative hyperglycemia in a swine model of surgical stress. [PDF]

Bioelectron Med
Song W, Qanud K, Thompson DA, Huston JM, Zanos S.   +4 more
europepmc   +1 more source

The foveal and para‐central spectral sensitivities in man [PDF]

, 1951
R. A. Weale
openalex   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source