Results 41 to 50 of about 3,327,512 (288)

Sensitivity analysis in economic evaluation: an audit of NICE current practice and a review of its use and value in decision-making

Health Technology Assessment, 2009
Objectives: To determine how we define good practice in sensitivity analysis in general and probabilistic sensitivity analysis (PSA) in particular, and to what extent it has been adhered to in the independent economic evaluations undertaken for the ...
L Andronis, P Barton, S Bryan
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Organization profit sensitivity analysis

Путеводитель предпринимателя
Sensitivity analysis has a wide application in modern conditions. This article reveals the possible variants of its practical use. One of the directions of sensitivity analysis is associated with assessing the impact of factors on the organization profit
I. V. Semina, V. S. Kiseleva
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Metamodel construction for sensitivity analysis

ESAIM: Proceedings and Surveys, 2017
We propose to estimate a metamodel and the sensitivity indices of a complex model m in the Gaussian regression framework. Our approach combines methods for sensitivity analysis of complex models and statistical tools for sparse non-parametric estimation ...
Huet Sylvie, Taupin Marie-Luce
doaj   +1 more source

Introspective Analysis: Context-Sensitivity, Across the Board [PDF]

, 2014
Context-sensitivity is the primary approach for adding more precision to a points-to analysis, while hopefully also maintaining scalability. An oft-reported problem with context-sensitive analyses, however, is that they are bi-modal: either the analysis ...
George Balatsouras, Yannis Smaragdakis, George Kastrinis, Kastrinis, George, Smaragdakis, Yannis, Balatsouras, George   +5 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

WOOD AND CHARCOAL PRODUCTION IN THE KILN-FURNACE SYSTEM: HOW DO THE COSTS AND REVENUES VARIATION AFFECT ECONOMIC FEASIBILITY?

Revista Árvore, 2021
Traditional methods of economic evaluation of wood and charcoal production projects are based on indicators analysis, however, they are subject to market variations and uncertainties. The study was carried out in the city of Lamim, Minas Gerais State, to
Bruno Leão Said Schettini, Laércio Antônio Gonçalves Jacovine, Carlos Moreira Miquelino Eleto Torres, Angélica de Cássia Oliveira Carneiro, Paulo Henrique Villanova, Samuel José Silva Soares da Rocha, Maria Paula Miranda Xavier Rufino, Renato Vinícius Oliveira Castro   +7 more
doaj   +1 more source

Sensitivity Analysis in OLAP Databases

Proceedings of the 20th International Conference on Enterprise Information Systems, 2018
The theoretical underpinnings under which sensitivity analysis is valid in OLAP databases are dealt with in this paper. Sensitivity analysis is considered to be the reverse of explanation generation in diagnostic reasoning. Our exposition differentiates between sensitivity analysis in systems of purely drill-down equation and mixed systems of equations
Caron, Emiel, Daniels, Hennie
openaire   +2 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source