Results 141 to 150 of about 2,654,059 (402)

Sensitivity, specificity and clinical cut-off point of the Persian short form version of the Female Sexual Function Index (FSFI-6) [PDF]

Payesh
Objective(s): Although the psychometric properties of the Persian version of the short form of the Female Sexual Function Scale (FSFI-6) was studied, the sensitivity and specificity of the Persian version of this instrument have not been investigated ...
Raziyeh Maasoumi, Shadi Sabetghadam, Parisa Samadi, Malihe Nasiri   +3 more
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

To determine the diagnostic accuracy of visual inspection of cervix with acetic acid as a screening tool to detect preinvasive cervical cancer – A meta-analysis

Journal of Family Medicine and Primary Care
This meta-analysis was done to estimate the efficacy of visual inspection of the cervix with acetic acid (VIA) to screen for the preinvasive stage of carcinoma cervix.
Atima Bharti, Rani Hansda, Ritika Bala, Amit Kumar   +3 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Sensitivity and specificity in prevalence studies: The importance of considering uncertainty [PDF]

, 2020
Rafael Izbicki, Márcio Alves Diniz, Leonardo Soares Bastos   +2 more
openalex   +1 more source

Specific Deletion of CASK in Pancreatic β Cells Affects Glucose Homeostasis and Improves Insulin Sensitivity in Obese Mice by Reducing Hyperinsulinemia Running Title: β Cell CASK Deletion Reduces Hyperinsulinemia [PDF]

, 2021
Xingjing Liu, Peng Sun, Qingzhao Yuan, Jinyang Xie, Ting Xiao, Kai Zhang, Xiu Chen, Yao Wang, Yuan Li, Xiao Han   +9 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Screening Characteristics of Ultrasonography in Detection of Ankle Fractures

Emergency, 2016
Introduction: Ankle fracture is one of the most common joint fractures. X-ray and physical examination are itsmain methods of diagnosis. Recently, ultrasonography (US) is considered as a simple and non-invasive methodof fracture diagnosis.
Majid Shojaee, Farhad Hakimzadeh, Parisa Mohammadi, Anita Sabzghabaei, Mohammad Manouchehrifar, Ali Arhami Dolatabadi   +5 more
doaj  

The influence of anatomical location on the accuracy of tonsillolith diagnosis on panoramic radiographs

Acta Scientiarum. Health Sciences
This study aimed to analyze the influence of anatomical location regarding the accuracy of the diagnosis of tonsilloliths on panoramic radiographs.Of 2022 digital panoramic radiographs analyzed, 181 presented tonsilloliths.
Matheus Herreira-Ferreira, Gustavo Nascimento de Souza-Pinto, Fernanda Chiguti Yamashita, Fernanda Silvestre, Breno Gabriel da Silva, Elen de Souza Tolentino, Mariliani Chicarelli, Lilian Cristina Vessoni Iwaki   +7 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source