Results 141 to 150 of about 1,511,556 (290)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Sensitivity /specificity–probability cut off plot.

, 2018
Sensitivity /specificity–probability cut off plot.
R. K. De Silva (5617187), A. Samaranayaka (5617193), W. A. M. U. L. Abeyasinghe (5617196), B. S. M. S. Siriwardena (5617190), W. M. Tilakaratne (5617199)   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Forest plots for sensitivity and specificity.

, 2018
Forest plots for sensitivity and specificity.
Ying Ba (5883845), Jian-ling Du (3416783), Qian Xing (3416804), Hao Wang (39217)   +3 more
core   +1 more source

To determine the diagnostic accuracy of visual inspection of cervix with acetic acid as a screening tool to detect preinvasive cervical cancer – A meta-analysis

Journal of Family Medicine and Primary Care
This meta-analysis was done to estimate the efficacy of visual inspection of the cervix with acetic acid (VIA) to screen for the preinvasive stage of carcinoma cervix.
Atima Bharti, Rani Hansda, Ritika Bala, Amit Kumar   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Sensitivity and Specificity for the tested algorithms.

, 2012
Sensitivity and Specificity for the tested algorithms.
Fabio Bagalà (164111), Jochen Klenk (164144), Clemens Becker (164116), Lorenzo Chiari (164125), Kamiar Aminian (164128), Wiebren Zijlstra (164138), Angelo Cappello (164122), Jeffrey M. Hausdorff (164133)   +7 more
core   +1 more source

Shortened questionnaires to assess anxiety and depression during in-hospital rehabilitation: clinical validation and cutoff scores

Neuropsychiatric Disease and Treatment, 2016
Giorgio Bertolotti,1 Loretta Moroni,1 Roberto Burro,2 Antonio Spanevello,3 Roberto FE Pedretti,4 Giandomenico Giorgetti5 1Psychology Unit, Salvatore Maugeri Foundation, IRCCS, Scientific Institute, Tradate, 2Department of Human Sciences &ndash ...
Bertolotti G, Moroni L, Burro R, Spanevello A, Pedretti RFE, Giorgetti G   +5 more
doaj  

Sensitivity and specificity of the trichoscopy

Indian Journal of Dermatology, Venereology, and Leprology, 2012
Elzbieta, Kowalska-Oledzka, Monika, Slowinska, Adriana, Rakowska   +2 more
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source