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Sensitive and specific CRISPR diagnostics

Science, 2017
CRISPR Technology Methods are needed that can easily detect nucleic acids that signal the presence of pathogens, even at very low levels. Gootenberg et al. combined the allele-specific sensing ability of CRISPR-Cas13a with recombinase polymerase amplification methods to detect specific RNA and DNA sequences.
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Sensitivity and specificity of elastase

Digestive Diseases and Sciences, 1988
J, Charneau, O, Douay, A, Daver, J, Boyer +3 more
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Sensitivities and Specificities of Diagnostic Tests

JAMA: The Journal of the American Medical Association, 1982
To the Editor.— The article by Harris on "The Hazards of Bedside Bayes" (1981;236:2602) presents an important caution. However, it misrepresents the inherent variability in data on diagnostic tests that can be collected in well-designed studies, and may exaggerate the effective variability of data on tests now in the literature.
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Rethinking sensitivity and specificity