Results 191 to 200 of about 2,048,624 (310)

Clinical Decision-Making: Between Scientific Precision and Human Responsibility How the Physician Navigates Between Sensitivity and Specificity to Make the Best Decision for the Patient. [PDF]

Linacre Q
Cicerone GC, Jean Tihan E, Serban GM.
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A noninferiority trial comparing the sensitivity and specificity of <i>Tritrichomonas foetus</i> RT-rtPCR using 0.9% sterile saline versus PBS as transport medium. [PDF]

J Vet Diagn Invest
Jumper TM, Thoresen M, King EH, Loy DS, Loy JD, Smith DR.   +5 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Diagnostic value, sensitivity and specificity of CT, MRI, and PET in evaluation of cartilage invasion in laryngeal and hypopharyngeal cancer. [PDF]

Sci Rep
Thurnheer SE, Rupp NJ, Balermpas P, Hüllner MW, Morand GB.   +4 more
europepmc   +1 more source

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Sensitivity and specificity of Gene Xpert Ultra in extrapulmonary tuberculosis (EPTB). [PDF]

Lung India
Prakash AK, Ramakrishnan GDA.
europepmc   +1 more source

Diagnostic tests (1) – sensitivity and specificity [PDF]

Phlebology: The Journal of Venous Disease, 2012
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

MRI and MRA Sensitivity and Specificity for Accurate Diagnosis of Labral Tear for Patients Undergoing Hip Arthroscopy With Concomitant Periacetabular Osteotomy. [PDF]

Orthop J Sports Med
Zhang Y, Ellis T, Kollmorgen RC, Shkoukani Z, Martin RL.   +4 more
europepmc   +1 more source