Coexistence of critical sensitivity and subcritical specificity can yield optimal population coding [PDF]
The vicinity of phase transitions selectively amplifies weak stimuli, yielding optimal sensitivity to distinguish external input. Along with this enhanced sensitivity, enhanced levels of fluctuations at criticality reduce the specificity of the response.
Gollo, Leonardo L.
arxiv +3 more sources
Estimating sensitivity and specificity of diagnostic tests using latent class models that account for conditional dependence between tests: a simulation study [PDF]
BACKGROUND: Latent class models are increasingly used to estimate the sensitivity and specificity of diagnostic tests in the absence of a gold standard, and are commonly fitted using Bayesian methods.
Baerenbold, Oliver+3 more
core +1 more source
Sensitivity and specificity of point-of-care circulating Cathodic antigen test before and after praziquantel treatment in diagnosing Schistosoma mansoni infection in adult population co-infected with human immunodeficiency virus-1, North-Western Tanzania. [PDF]
BACKGROUND: The effect of Human Immunodeficiency Virus-1 (HIV-1) on CD4+ Th2 cells is hypothesized to affect parasitological diagnosis of Schistosoma mansoni using Kato Katz technique.
A Danso-Appiah+36 more
core +1 more source
A likelihood based sensitivity analysis for publication bias on summary ROC in meta-analysis of diagnostic test accuracy [PDF]
In meta-analysis of diagnostic test accuracy, summary receiver operating characteristic (SROC) is a recommended method to summarize the discriminant capacity of a diagnostic test in the presence of study-specific cutoff values and the area under the SROC (SAUC) gives the aggregate measure of test accuracy.
arxiv +1 more source
What are sensitivity and specificity? [PDF]
Whenever we create a test to screen for a disease, to detect an abnormality or to measure a physiological parameter such as blood pressure (BP), we must determine how valid that test is—does it measure what it sets out to measure accurately? There are lots of factors that combine to describe how valid a test is: sensitivity and specificity are two such
Amelia Swift+2 more
openaire +3 more sources
Background: Brøset Violence Checklist (BVC) and Dynamic Appraisal of Situational Aggression-Inpatient Version (DASA-IV) are risk assessment instruments of violence that nurses can use in psychiatric services, but their accuracy of the instruments in ...
Wahyu Yuniati+2 more
doaj +1 more source
Sensitivity and Specificity of Information Criteria [PDF]
Information criteria (ICs) based on penalized likelihood, such as Akaike's Information Criterion (AIC), the Bayesian Information Criterion (BIC), and sample-size-adjusted versions of them, are widely used for model selection in health and biological research.
Dziak, John J+4 more
openaire +6 more sources
Validity and practical utility of accelerometry for the measurement of in-hand physical activity in horses [PDF]
Background: Accelerometers are valid, practical and reliable tools for the measurement of habitual physical activity (PA). Quantification of PA in horses is desirable for use in research and clinical settings. The objective of this study was to evaluate
Carnwath, J.+6 more
core +2 more sources
Uncertain Times: Clinical Decision-Making in Sickness and in Health
Introduction It is increasingly important for medical students to recognize the importance of uncertainty in clinical decision-making. At our institution we implemented a three-part session at the beginning of second-year medical school, prior to organ ...
Laura Willett
doaj +1 more source
Sensitivity and specificity of diagnostic tests for Lassa fever: a systematic review. [PDF]
BACKGROUND: Lassa fever virus has been enlisted as a priority pathogen of epidemic potential by the World Health organization Research and Development (WHO R & D) Blueprint. Diagnostics play a crucial role in epidemic preparedness. This systematic review
Brangel, Polina+3 more
core +1 more source