Results 41 to 50 of about 2,048,624 (310)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Performance of nested-RT-PCR assays for Zika and Dengue detection

Acta Scientiarum: Biological Sciences
Arboviruses represent a public health problem in developing countries. Accurate diagnosis has been challenging in Dengue virus endemic countries, especially since the introduction of the Zika and Chikungunya viruses.
José Henrique Francisco Roma, Rachel Cruz Alves, Stefhano Luis Candido, Valéria Dutra, Luciano Nakazato, Renata Dezengrini-Slhessarenko, Juliana Helena Chavez-Pavoni, Mariângela Ribeiro Resende   +7 more
doaj   +1 more source

Comparison of bulk milk antibody and youngstock serology screens for determining herd status for Bovine Viral Diarrhoea Virus [PDF]

, 2016
BACKGROUND: This paper examines the use of Bulk Milk antibody (BM Ab), Youngstock (YS) serology (Check Tests) and Bulk Milk PCR (BM PCR) for determining the presence or absence of animals persistently infected (PI) with Bovine Viral Diarrhoea Virus (BVDV)
A Lindberg, A Moerman, A Uttenthal, AL Lindberg, AW Stott, B Fredriksen, C Wray, E Peterhans, G Pritchard, GJ Gunn, H Houe, H Houe, H Houe, H Houe, H Houe, J Brownlie, JA Ellis, Joe Brownlie, LN Potgieter, MF Chamorro, MH Mars, MR McGowan, P Presi, P Virakul, PS Valle, R Bennett, R Niskanen, R Niskanen, RE Booth, RE Booth, Richard E. Booth, RM Barlow, S Edwards, S Sarrazin, TW Drew, V Moennig   +35 more
core   +3 more sources

Functional Gait Assessment Tests in Elderly: A Systematic Review

Caspian Journal of Neurological Sciences, 2023
Background: Due to the mobility problems of the elderly, it is better to use low-cost and applicable methods in any place, which do not require expertise to measure gait. One of these ubiquitous methods is functional gait assessment (FGA).
Ali Asghar Norasteh, Esmail Balayi, Hamed Zarei   +2 more
doaj  

Posterior breast cancer: Mammographic and ultrasonographic features [PDF]

Vojnosanitetski Pregled, 2013
Background/Aim. Posterior breast cancers are located in the prepectoral region of the breast. Owing to this distinctive anatomical localization, physical examination and mammographic or ultrasonographic evaluation can be difficult.
Janković Ana, Nadrljanski Mirjan, Plešinac-Karapandžić Vesna, Ivanović Nebojša, Radojičić Zoran, Milošević Zorica   +5 more
doaj   +1 more source

Sensitivity and specificity of detection methods for erythropoietin doping in cyclists [PDF]

, 2019
Recombinant human erythropoietin (rHuEPO) is used as doping a substance. Anti-doping efforts include urine and blood testing and monitoring the athlete biological passport (ABP).
Burggraaf, Jacobus, Cohen, Adam F, Daniels, Johannes MA, Gal, Pim, Heuberger, Jules AAC, Hon, Olivier, Post, Titiaan E, Ram, Herman, Rotmans, Joris I, Stuurman, Frederik E, Van Eenoo, Peter   +10 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Sensitivity and specificity of the detection of spondylodiscitis by conventional radiography

Ulusal Romatoloji Dergisi
Objective: Diagnosis of spondylodiscitis is usually possible radiographically with magnetic resonance imaging (MRI). However, the first imaging method evaluated in daily practice is conventional radiography.
Zehra Özsoy, Emrach Chousein, Gizem Ayan, Güllü Sandal Uzun, Mustafa Ekici, Erdinç Ünaldı, Büşra Fırlatan, Gözde Sevgi Kart Bayram, Buğu Bulat, Levent Kılıç   +9 more
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Sensitivity and specificity of median nerve ultrasonography in diagnosis of carpal tunnel syndrome

International Journal of General Medicine, 2012
Mohammad Yazdchi1, Mohammad Kazem Tarzemani2, Haleh Mikaeili3, Hormoz Ayromlu1, Hooman Ebadi11Neuroscience Research Center, 2Department of Radiology, 3Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz ...
Yazdchi M, Tarzemani MK, Mikaeili H, Ayromlu H, Ebadi H   +4 more
doaj