Results 61 to 70 of about 2,048,624 (310)

Sensitivity and Specificity of Photoaptamer Probes [PDF]

Molecular & Cellular Proteomics, 2003
The potential of photoaptamers as proteomic probes was investigated. Photoaptamers are defined as aptamers that bear photocross-linking functionality, in this report, 5-bromo-2'-deoxyuridine. A key question regarding the use of photoaptamer probes is the specificity of the cross-linking reaction.
Drew, Smith, Brian D, Collins, James, Heil, Tad H, Koch   +3 more
openaire   +2 more sources

Dual time-point FDG PET/CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area [PDF]

, 2010
Objective. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) is an accurate non-invasive imaging test for differentiating benign from malignant solitary pulmonary nodules (SPNs).
Maes, Alex, Pottel, Hans, Sathekge, Mike Machab, Stoltz, Anton, Van De Wiele, Christophe   +4 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Determination of a cutoff for noise sensitivity: Psychometric evaluation of the Turkish Noise Sensitivity Questionnaire (Tr-NoiSeQ)

Noise and Health, 2022
Context: There is a need for a clear cutoff to use noise sensitivity (NS) scale as a prediagnostic tool in research and clinical use. Aims: Noise sensitivity questionnaire (NoiSeQ) was adapted into Turkish language (Tr-NoiSeQ); validity and reliability ...
Asuman Alniacik, Eda Çakmak
doaj   +1 more source

Post-Mortem diagnosis of dementia by informant interview. [PDF]

, 2010
The diagnosis of normal cognition or dementia in the Brazilian Brain Bank of the Aging Brain Study Group (BBBABSG) has relied on postmortem interview with an informant. Objectives:To ascertain the sensitivity and specificity of postmortem diagnosis based
Balbino, Érika Silvério, Battela, Camila, Brucki, Sonia Maria Dozzi, Campora, Flávia, Damin, Antonio Eduardo, Farfel, José Marcelo, Ferretti, Renata Eloah de Lucena, Grinberg, Lea Tenenholz, Jacob-Filho, Wilson, Leite, Renata Elaine Paraiso, Lima, Maria do Carmo de Ascenção, Moreira, Eliza Guccione, Morillo, Lilian Schafirovits, Nitrini, Ricardo, Pasqualucci, Carlos Augusto, Perroco, Tibor Rilho, Rosemberg, Sérgio, Ruiz, Lumena, Saldiva, Paulo Hilário Nascimento, Suemoto, Claudia Kimie   +19 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Joint modeling of sensitivity and specificity [PDF]

Statistics in Medicine, 2008
AbstractSensitivity and specificity are two customary performance measures associated with medical diagnostic tests. Typically, they are modeled independently as a function of risk factors using logistic regression, which provides estimated functions for these probabilities.
Gavino, Puggioni, Alan E, Gelfand, Joann G, Elmore   +2 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Accuracy of magnetic resonance studies in the detection of chondral and labral lesions in femoroacetabular impingement : systematic review and meta-analysis [PDF]

, 2017
Background: Several types of Magnetic resonance imaging (MRI) are commonly used in imaging of femoroacetabular impingement (FAI), however till now there are no clear protocols and recommendations for each type.
A Aprato, A Giovagnoni, A. M. Saied, AB Gonzalez Gil, AC Johnson, B Bittersohl, C Czerny, C. Redant, CM McGuire, CN Petchprapa, CW Pfirrmann, CY Tian, D Moher, DA Rubin, DB Banks, DN Mintz, E Perdikakis, E Zaragoza, E. A. Audenaert, EA Audenaert, G Reurink, GM Riley, H Eijer, J Zamora, J. Anthonissen, JA Keeney, JK Chakraverty, K Hack, K Hajian-Tilaki, KA Jung, LA Anderson, LB Laborie, M Leunig, M Sahin, M. El-Batouty, M. R. El-Lakkany, MB Zlatkin, MR Schmid, PF Whiting, R Ganz, R Lattanzi, R Lattanzi, R Sutter, R. Verdonk, SL James, TO Smith, TO Smith, U Studler, W. A. El-Adl, WB Morrison, YJ Kim   +50 more
core   +1 more source