Results 71 to 80 of about 2,163,703 (333)

Proper Estimation of Sensitivity and Specificity [PDF]

open access: yesClinical and Vaccine Immunology, 2006
I write to express concern about the diagnostic accuracy statements of Eda et. al. concerning a new Johne's disease enzyme-linked immunosorbent assay (ELISA) (2). The diagnostic sensitivity of this new ELISA for bovine paratuberculosis, reported to be 100%, was based on only 64 (according to the Materials and Methods) or 51 (according to the Results)
openaire   +2 more sources

Sensitivity and specificity of EUS in staging.

open access: yes, 2016
A), B) are sensitivity and specificity of EUS in staging T1; C), D) are sensitivity and specificity of EUS in staging T1a; E), F) are sensitivity and specificity of EUS in staging T1b; G), H) are sensitivity and specificity of EUS in staging T2; I), J ...
Lin-na Luo (3157512)   +11 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The specific suppression of contact sensitivity [PDF]

open access: yesArthritis & Rheumatism, 1978
The ability of 2,4,6 trinitrobenzenesulfonic acid (TNBS)-induced regulatory cells to modulate the generation of contact sensitivity (CS) to picryl chloride has been studied. We have confirmed that such suppressor cells can modulate CS and have extended these observations to demonstrate that suppressor factors, liberated by suppressor cells in ...
M I, Greene, A, Pierres, B, Benacerraf
openaire   +2 more sources

Sensitivity and specificity plots.

open access: yes, 2016
To determine the optimal cut-off point, sensitivity and specificity are plotted against the threshold (A), the optimal cut-off point is present at 0.52. The sensitivity is plotted against 1—specificity for all cutoff values of the PLS-DA model in the ROC
Danique Vervoort (2822603)   +4 more
core   +1 more source

Sensitivity vs specificity at ≥20 days.

open access: yes, 2022
Sensitivity against specificity for the kits tested (IgG only, and positive or negative result for the LumiraDx assay). For each kit the ≥20 days post symptom onset sensitivity is shown.
Frauke Muecksch (11084312)   +13 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Using samples to estimate the sensitivity and specificity of a surveillance process

open access: yes, 2008
Determining sensitivity and specificity of a postoperative infection surveillance process is a difficult undertaking. Because postoperative infections are rare, vast numbers of negative results exist, and it is often not reasonable to assess them all ...
McElwain, D. L. Sean   +6 more
core   +1 more source

Sensitivity and specificity analysis.

open access: yes, 2020
(A) The sensitivity achieved by the Bayesian model on the simulated dataset (n = 92) is shown on the x-axis for various simulated differences Δ on the y-axis. The standardized effect size dC (Cohen’s d) is depicted next to the bars.
Hans-Ulrich Klein (158006)   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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