Results 71 to 80 of about 1,462,497 (283)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Sensitivity and Specificity plot.

, 2014
The plot compares sensitivity and specificity of the developed predictive models, to determine effective classifier for identifying positive and negative instances.
Zeenia Jagga (564251), Dinesh Gupta (19194)   +1 more
core   +1 more source

Sensitivity vs specificity at ≥20 days.

, 2022
Sensitivity against specificity for the kits tested (IgG only, and positive or negative result for the LumiraDx assay). For each kit the ≥20 days post symptom onset sensitivity is shown.
Frauke Muecksch (11084312), Kirsty McCance (12329276), Becky Batchelor (12329279), Harriet Hale (12329282), Lindsay McDonald (5447573), Elizabeth Furrie (12329285), Azul Zorzoli (3191493), Paul D. Bieniasz (9137637), Theodora Hatziioannou (220814), Jennifer Simpson (2927841), Charu Chopra (12329288), Sara Jenks (10532435), Helen Wise (129747), Kate Templeton (368206)   +13 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Comparative Study Between Pap Smear and Visual Inspection with Acetic Acid in Screening of Cervical Intraepithelial Neoplasia and Cervical Cancer at a Tertiary Maternity Hospital (Erbil/Iraq)

Advanced Medical Journal
Background and objectives: Global concern persists over cervical cancer, demanding efficient early detection methods. The aim of the study was to assess the diagnostic efficacy of Pap smear and visual inspection with acetic acid in detecting cervical ...
Shkofa Khalid Mohammed, Trifa Yousif Mutalib   +1 more
doaj   +1 more source

Sensitivity and specificity analysis.

, 2018
Sensitivity and specificity analysis.
Jose Luis Ramirez-GarciaLuna (3873601), Mario Aurelio Martínez-Jiménez (5963564), Eleazar Samuel Kolosovas-Machuca (5963567), Justin Drager (5963570), Francisco Javier González (5963573)   +4 more
core   +1 more source

Diagnosing synaesthesia with online colour pickers: Maximising sensitivity and specificity [PDF]

, 2013
The most commonly used method for formally assessing grapheme-colour synaesthesia (i.e., experiencing colours in response to letter and/or number stimuli) involves selecting colours from a large colour palette on several occasions and measuring ...
Rothen, Nicolas, Nicolas Rothen (264938), Nicolas Rothen, Jamie Ward (4460812), Ward, Jamie, Christoph Witzel, Seth, Anil K., Christoph Witzel (3948908), Anil K Seth, Jamie Ward, Witzel, Christoph, Anil Seth (4460704), Seth, Anil, Ward, James   +13 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Clinical and laboratory signs associated to serious dengue disease in hospitalized children

Jornal de Pediatria (Versão em Português), 2016
Objective: To evaluate the validity of clinical and laboratory signs to serious dengue disease in hospitalized children. Methods: Retrospective cohort of children (19 and negative likelihood ratio
Sheila Moura Pone, Yara Hahr Marques Hökerberg, Raquel de Vasconcellos Carvalhaes de Oliveira, Regina Paiva Daumas, Tamiris Moura Pone, Marcos Vinicius da Silva Pone, Patricia Brasil   +6 more
doaj   +1 more source