Results 91 to 100 of about 1,511,556 (290)

Sensitivity and specificity in detecting bimanual tapping.

open access: yes, 2014
The sensitivity and specificity (sensitivity/specificity) in detecting if a task was performed with only the right index finger (unimanual), or with both index fingers (bimanual) was computed for all participants using a simple threshold approach (bold ...
Anna Zilverstand (510773)   +4 more
core   +1 more source

Screening Characteristics of Ultrasonography in Detection of Ankle Fractures

open access: yesArchives of Academic Emergency Medicine, 2018
Introduction: Ankle fracture is one of the most common joint fractures. X-ray and physical examination are its main methods of diagnosis. Recently, ultrasonography (US) is considered as a simple and non-invasive method of fracture diagnosis.
Majid Shojaee   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The sensitivity, specificity and precision.

open access: yes, 2015
The sensitivity, specificity and precision of both sets separately and combined when six votes are required. The number of others refers to sound events that are not screams.The sensitivity, specificity and precision.
M. Kashiha (732017)   +10 more
core   +1 more source

Forest plots of pooled sensitivity and specificity.

open access: yes, 2022
Forest plots of pooled sensitivity and specificity.
Xiao Ge (3909412)   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Sensitivity and Specificity of Each Tool.

open access: yes, 2016
Sensitivity and Specificity of Each Tool.
Encarnación Blanco-Reina (3372848)   +6 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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