Results 91 to 100 of about 2,163,703 (333)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Sensitivity and specificity comparison.

, 2012
Sensitivity and specificity comparison.
Ravi Sanka (124354), Zhengyuan Wang (158458), John Martin (1716), Nihar Sheth (158452), Joshua Orvis (48228), Erica Sodergren (48852), George M. Weinstock (43281), Sarah Young (158443), Makedonka Mitreva (27680), Sean Sykes (158441), Karthik Kota (158445)   +10 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Improving Sensitivity and Specificity of Capturing and Detecting Targeted Cancer Cells with Anti-Biofouling Polymer Coated Magnetic Iron Oxide Nanoparticles

Colloids and Surfaces B: Biointerfaces, 2016
Detecting circulating tumor cells (CTCs) with high sensitivity and specificity is critical to management of metastatic cancers. Although immuno-magnetic technology for in vitro detection of CTCs has shown promising potential for clinical applications ...
Run Lin, Yuancheng Li, T. MacDonald, Hui-Fen Wu, J. Provenzale, Xingui Peng, Jing Huang, Liya Wang, Andrew Wang, Jian-yong Yang, H. Mao   +10 more
semanticscholar   +1 more source

Sensitivity and specificity parameters.

, 2018
Sensitivity and specificity parameters.
Anna Smelik (5745920), Lukasz Szarpak (4063414), Kurt Ruetzler (2793979), Maja Copik (5745917), Piotr Palczynski (5745908), Hanna Misiolek (5745914), Szymon Bialka (5745911)   +6 more
core   +1 more source

Sensitivity and Specificity of Troponins in AMI

, 2023
A review was carried out to relate the presence of Acute Myocardial Infarction (AMI) by determining biomarkers, detailing their sensitivity and specificity, with the aim of determining the specificity and sensitivity of biomarkers in AMI.
Carmen, María del, Isabel, Fong Betancourt María, Labrada, Yabor, Elsy, Labrada González   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 2016
Sensitivity and/or specificity of the in vivo erythrocyte micronucleus (MN) and transgenic rodent mutation (TGR) tests to detect rodent carcinogens and non-carcinogens were investigated.
T. Morita, S. Hamada, K. Masumura, A. Wakata, J. Maniwa, H. Takasawa, K. Yasunaga, Tsuneo Hashizume, M. Honma   +8 more
semanticscholar   +1 more source

Sensitivity and Specificity analysis.

, 2016
Sensitivity and Specificity analysis.
Keshendree Moodley (2805811), Lindi-Marie Coetzee (2805814), Deborah Kim Glencross (2805808)   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source