Results 111 to 120 of about 2,163,703 (333)
, 2009 The aim of the study was to determine the sensitivity and specificity for typical abdominal injuries after major blunt trauma in postmortem multislice computed tomography (MSCT) and magnetic resonance imaging (MRI)
Spendlove, Danny +6 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Screening Characteristics of Ultrasonography in Detection of Ankle Fractures
Archives of Academic Emergency Medicine, 2018 Introduction: Ankle fracture is one of the most common joint fractures. X-ray and physical examination are its main methods of diagnosis. Recently, ultrasonography (US) is considered as a simple and non-invasive method of fracture diagnosis.
Majid Shojaee +5 more
doaj +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Diagnostic Performance of Arm Circumference Compared to Other Indicators for Detecting Sarcopenia in Older Adults [PDF]
Annals of Geriatric Medicine and ResearchBackground To evaluate the accuracy of arm circumference (AC) compared with other anthropometric and functional indicators as a predictor of sarcopenia risk in community-dwelling older adults.
Brena Leticia Gomes de Paiva +7 more
doaj +1 more source
Mechanisms of Sensitivity and Specificity in Olfaction
Cold Spring Harbor Symposia on Quantitative Biology, 1992 The sensitivity and specificity of the mammalian olfactory system is the result of the contributions at the anatomical, cellular, and biochemical levels. The recent identification of a large gene family encoding putative olfactory receptors suggests that genetic diversity may play an important role in this system. Future challenges lie in understanding
openaire +2 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Clinical Epidemiology, 2019 Ren Jie Robert Yao,1 Jason G Andrade,1 Marc W Deyell,1 Heather Jackson,2 Finlay A McAlister,3 Nathaniel M Hawkins11Division of Cardiology, University of British Columbia, Vancouver, Canada; 2Cardiac Services British Columbia, Vancouver, Canada; 3Division
Yao RJR +5 more
doaj
, 2005 OBJECTIVES: To determine the value of computer-aided detection (CAD) for breast cancer screening. DESIGN: Two sets of mammograms with known outcomes were used in two studies.
Champness, J +9 more
core +1 more source