Results 101 to 110 of about 2,048,624 (310)

Screening Characteristics of Ultrasonography in Detection of Ankle Fractures

Archives of Academic Emergency Medicine, 2018
Introduction: Ankle fracture is one of the most common joint fractures. X-ray and physical examination are its main methods of diagnosis. Recently, ultrasonography (US) is considered as a simple and non-invasive method of fracture diagnosis.
Majid Shojaee, Farhad Hakimzadeh, Parisa Mohammadi, Anita Sabzghabaei, Mohammad Manouchehrifar, Ali Arhami Dolatabadi   +5 more
doaj   +1 more source

Discriminating active from latent tuberculosis in patients presenting to community clinics. [PDF]

, 2012
BACKGROUND: Because of the high global prevalence of latent TB infection (LTBI), a key challenge in endemic settings is distinguishing patients with active TB from patients with overlapping clinical symptoms without active TB but with co-existing LTBI ...
Agranoff, DD, Athanasakis, D, Battaglia, F, Ely, BK, Evans, CA, Fernandez-Reyes, D, Friedland, JS, Gilman, RH, Montoya, R, Sandhu, G, Valencia, T   +10 more
core   +5 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Dedication [PDF]

, 2001
OBJECTIVES: The aims of this study were to examine and compare the predictive validity of 4 risk assessment scales used for the prediction of pressure ulcer (PrU) development and to identify risk factors.
Källman, Ulrika, Lindgren, Margareta
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Diagnostic Performance of Arm Circumference Compared to Other Indicators for Detecting Sarcopenia in Older Adults [PDF]

Annals of Geriatric Medicine and Research
Background To evaluate the accuracy of arm circumference (AC) compared with other anthropometric and functional indicators as a predictor of sarcopenia risk in community-dwelling older adults.
Brena Leticia Gomes de Paiva, Claudia Porto Sabino Pinho Ramiro, Cyro Rego Cabral Junior, Fabiana Andrea Moura, Enaiane Cristina Menezes, Gabriel Soares Bádue, Müller Ribeiro-Andrade, João Araújo Barros-Neto   +7 more
doaj   +1 more source

Proper Estimation of Sensitivity and Specificity [PDF]

Clinical and Vaccine Immunology, 2006
I write to express concern about the diagnostic accuracy statements of Eda et. al. concerning a new Johne's disease enzyme-linked immunosorbent assay (ELISA) (2). The diagnostic sensitivity of this new ELISA for bovine paratuberculosis, reported to be 100%, was based on only 64 (according to the Materials and Methods) or 51 (according to the Results)
openaire   +2 more sources

Examination of Acid-Fast Bacilli in Sputum Using Modified Light Microscope with Homemade Light Emitting Diode Additional Attachment [PDF]

, 2011
Typical clinical symptoms and chest X-ray is a marker of Tuberculosis (TB) sufferers. However, the diagnosis of TB in adults should be supported by microscopic examination.
Damian P. Hruszkewycz (1802131), Louise M. Guard (1469071), Matthew J. Chalkley (1926736), Michael K. Takase (1371342), Nilay Hazari (1469062), Peter Hofmann (624654), Timothy J. Schmeier (1845007)   +6 more
core   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Sensitivity, specificity, positive and negative predictive values of identifying atrial fibrillation using administrative data: a systematic review and meta-analysis

Clinical Epidemiology, 2019
Ren Jie Robert Yao,1 Jason G Andrade,1 Marc W Deyell,1 Heather Jackson,2 Finlay A McAlister,3 Nathaniel M Hawkins11Division of Cardiology, University of British Columbia, Vancouver, Canada; 2Cardiac Services British Columbia, Vancouver, Canada; 3Division
Yao RJR, Andrade JG, Deyell MW, Jackson H, McAlister FA, Hawkins NM   +5 more
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