Results 121 to 130 of about 2,663,215 (302)

Short-Term Robustness of Production Management Systems: New Methodology [PDF]

open access: yes
This paper investigates the short-term robustness of production planning and control systems. This robustness is defined here as the systems ability to maintain short-term service probabilities (i.e., the probability that the fill rate remains within a ...
Gaury, E.G.A., Kleijnen, J.P.C.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hierarchical Blocking Control for Mitigating Cascading Failures in Power Systems with Wind Power Integration

open access: yesEnergies
The increasing uncertainty of wind power brings greater challenges to the control for mitigation of cascading failures. In order to minimize the risk of cascading failures in large-scale wind power systems at a lower economic cost, a multi-stage blocking
Lun Cheng   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Risk-sensitive control of cash management systems

open access: yesOperational Research, 2017
[EN] Firms manage cash for operational, precautionary and speculative purposes. Stat-of-the-art cash management models usually focus on cost minimization by means of a set of controlling bounds. In this paper, we propose a multiobjective model to control cash management systems with multiple accounts characterized by generalized cash flow processes. In
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Sensitivity Analysis and Distribution Factor Calculation under Power Network Branch Power Flow Exceedance

open access: yesEnergies
As the scale of power systems continue to expand and their structure becomes increasingly complex, it is likely that branch power flow exceedance may occur during the operation of power systems, posing threats to the safe and stable operation of entire ...
Shuqin Sun   +4 more
doaj   +1 more source

An application of eigenspace methods to symmetric flutter suppression [PDF]

open access: yes
An eigenspace assignment approach to the design of parameter insensitive control laws for linear multivariable systems is presented. The control design scheme utilizes flexibility in eigenvector assignments to reduce control system sensitivity to changes
Fennell, Robert E.
core   +1 more source

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