Results 81 to 90 of about 8,187,354 (351)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Electrochemiluminescence Mechanisms Investigated with Smartphone‐Based Sensor Data Modeling, Parameter Estimation and Sensitivity Analysis

open access: yesChemistryOpen, 2020
The present study introduces a unified framework combining a mechanistic model with a genetic algorithm (GA) for the parameter estimation of electrochemiluminescence (ECL) kinetics of the Ru(bpy)32+/TPrA system occurring in a smartphone‐based sensor. The
Dr. Elmer Ccopa Rivera   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity.

open access: yes, 2014
Background: Non-celiac gluten sensitivity (NCGS) is still an undefined syndrome with several unsettled issues despite the increasing awareness of its existence.
Bardella MT   +9 more
core   +1 more source

Sensitivity optimization in quantum parameter estimation [PDF]

open access: yes, 2001
We present a general framework for sensitivity optimization in quantum parameter estimation schemes based on continuous (indirect) observation of a dynamical system. As an illustrative example, we analyze the canonical scenario of monitoring the position
Doherty, A. C.   +6 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Active and adaptive case finding to estimate therapeutic program coverage for severe acute malnutrition: a capture-recapture study

open access: yesBMC Health Services Research, 2019
Background Coverage is an important indicator to assess both the performance and effectiveness of public health programs. Recommended methods for coverage estimation for the treatment of severe acute malnutrition (SAM) can involve active and adaptive ...
Sheila Isanaka   +5 more
doaj   +1 more source

Estimation of regional differences in wind erosion sensitivity in Hungary [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2015
In Hungary, wind erosion is one of the most serious natural hazards. Spatial and temporal variation in the factors that determine the location and intensity of wind erosion damage are not well known, nor are the regional and local sensitivities to ...
G. Mezősi   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy