Results 141 to 150 of about 6,464,851 (305)

Index 1916 [PDF]

open access: yes, 1916
This is volume 35 of the College of Wooster’s Index collection. The Index is the college’s yearbook, it includes an annual record of events at Wooster. This edition was published by the class of 1916.
Index Editors,
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The Determination of the Sensitivity of Refractive Index Sensors

open access: yesPhotonics
A new approach to determining the sensitivity of refractive index sensors is proposed. It has been shown that relative and absolute sensitivity show different results, and also, for the first time, it is demonstrated that relative sensitivity has ...
Ilya M. Efimov   +2 more
doaj   +1 more source

A Cross-Sectional Multicentre Study to Validate Insulin Sensitivity Index Cut-Offs for Detection of Metabolic Syndrome in Indian Adolescents with Type-1 Diabetes. [PDF]

open access: yesIndian J Endocrinol Metab, 2023
Oza C   +8 more
europepmc   +1 more source

Index 1944 [PDF]

open access: yes, 1944
This is the 1944 edition of the Index. The Index is written by student editors, and it is the college’s yearbook. It includes an annual record of events at Wooster.
Index Editors,
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

The visceral sensitivity index: A novel tool for measuring GI-symptom-specific anxiety in inflammatory bowel disease. [PDF]

open access: yesNeurogastroenterol Motil, 2022
Trieschmann K   +8 more
europepmc   +1 more source

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