Exploring the Sensitivity of Prodromal Dementia with Lewy Bodies Research Criteria
Brain Sciences, 2022 Dementia with Lewy bodies (DLB) is an insidious neurodegenerative disease characterised by a precipitous decline in cognition, sleep disturbances, motor impairment and psychiatric features. Recently, criteria for prodromal DLB (pDLB) including clinical features and biomarkers have been put forward to aid the classification and research of this ...
Joseph R. Phillips +5 more
openaire +4 more sources
Metabolic effects of mangosteen supplementation as an adjuvant to sitagliptin/metformin in newly diagnosed type 2 diabetes Iraqi patients [PDF]
PharmaciaType 2 diabetes mellitus often remains inadequately managed despite effective oral treatments. Mangosteen (Garcinia mangostana), abundant in xanthones, including α-mangostin, may have metabolic and insulin-sensitizing properties; however, clinical data ...
Mays Qays Habeeb +2 more
doaj +3 more sources
11 beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle [PDF]
, 2009 OBJECTIVE: Glucocorticoid excess is characterized by increased adiposity, skeletal myopathy, and insulin resistance, but the precise molecular mechanisms are unknown.
A. Yu +37 more
core +3 more sources
The immunohistochemical expression of leptin in lymph node metastasis from laryngeal squamous cell carcinoma (SCC) [PDF]
, 2020 Introduction: Leptin is a proteohormone produced predominantly by white adipocytes and primarily known for its key role in the control of food intake and sense of satiety.
D'Alessi S +7 more
core +1 more source
Activation of Liver X Receptor α Sensitizes Mice to T‐Cell Mediated Hepatitis
Hepatology Communications, 2020 Autoimmune hepatitis (AIH) is an inflammatory disease of the liver. Liver X receptors (LXRs), including the α and β isoforms, are previously known for their anti‐inflammatory activities.
Li Gao +14 more
doaj +1 more source
Telomere length as a predictor of response to Pioglitazone in patients with unremitted depression: a preliminary study. [PDF]
, 2016 We studied peripheral leukocyte telomere length (LTL) as a predictor of antidepressant response to PPAR-γ agonist in patients with unremitted depression.
Blackburn, E +4 more
core +1 more source
Diabetes, 2012 Whether the well-known metabolic switch AMP-activated protein kinase (AMPK) is involved in the insulin-sensitizing effect of calorie restriction (CR) is unclear.
Pei Wang +7 more
semanticscholar +1 more source
Capsaicin and TRPV1 Channels in the Cardiovascular System: The Role of Inflammation
Cells, 2021 Capsaicin is a potent agonist of the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel and is a common component found in the fruits of the genus Capsicum plants, which have been known to humanity and consumed in food for approximately 7000 ...
Sreepadaarchana Munjuluri +5 more
doaj +1 more source
Breast cancer as photodynamic therapy target: Enhanced therapeutic efficiency by overview of tumor complexity [PDF]
, 2014 Photodynamic therapy is a minimally invasive and clinically approved procedure for eliminating selected malignant cells with specific light activation of a photosensitizer agent.
Lamberti, María Julia +2 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source