Results 31 to 40 of about 92,833 (358)
p53 is required for chloroquine-induced atheroprotection but not insulin sensitization[S]
Journal of Lipid Research, 2010 An intact genotoxic stress response appears to be atheroprotective and insulin sensitizing. ATM, mutated in ataxia telangiectasia, is critical for the genotoxic stress response, and its deficiency is associated with accelerated atherosclerosis and ...
Babak Razani +2 more
doaj +1 more source
Frontiers in Physiology, 2021 LEP is a pleiotropic gene and the actions of leptin extend well beyond simply acting as the signal of the size of adipose tissue stores originally proposed.
Charles A. LeDuc +2 more
doaj +1 more source
Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine receptor-STAT3 pathway. [PDF]
PLoS ONE, 2012 This study was to investigate the effect of nicotine on insulin sensitivity and explore the underlying mechanisms. Treatment of Sprague-Dawley rats with nicotine (3 mg/kg/day) for 6 weeks reduced 43% body weight gain and 65% blood insulin level, but had ...
Tian-Ying Xu +6 more
doaj +1 more source
Role of adipokines in sarcopenia
Chinese Medical Journal, 2023 . Sarcopenia is an age-related disease that mainly involves decreases in muscle mass, muscle strength and muscle function. At the same time, the body fat content increases with aging, especially the visceral fat content.
Wenhao Lu +6 more
doaj +1 more source
Nutrition & Metabolism, 2011 Background Quercetin derivatives in onions have been regarded as the most important flavonoids to improve diabetic status in cells and animal models. The present study was aimed to examine the hypoglycemic and insulin-sensitizing capacity of onion peel ...
Kim Ji Yeon +4 more
doaj +1 more source
The potential role and application of PARP inhibitors in cancer treatment [PDF]
, 2009 Background: Since many anti-cancer agents act by inflicting DNA damage on tumour cells, there is increasing interest in the use of inhibitors of DNA repair to increase the cytotoxicity of these agents.
Chalmers, Anthony J
core +2 more sources
Kulturella Perspektiv, 2004 Pimples can, when they appear, claim much more space in life than just the spots in the face. For the one who is badly affected, pimples become central for the way in which the person acts, feels and experiences the world. The many hours in front of the
Linda Sturesson Witt
doaj +1 more source
Rosiglitazone Add-On in Treatment of Depressed Patients with Insulin Resistance: a Pilot Study
The Scientific World Journal, 2010 A number of cross-sectional studies have suggested an association between insulin resistance (IR) and affective disorders. However, limited data exist on potential changes in IR in a prospective treatment of depression. The present pilot study tested the
Natalie L. Rasgon +5 more
doaj +1 more source
Frontiers in Toxicology, 2022 Although their production was banned in the United States in 1977, polychlorinated biphenyls (PCBs) continue to pose significant risks to the developing nervous system.
Bianca Yaghoobi +9 more
doaj +1 more source
Increased hazard of myocardial infarction with insulin‐provision therapy in actively smoking patients with diabetes mellitus and stable ischemic heart disease: The BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) trial [PDF]
, 2017 Background In the BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) trial, randomization of diabetic patients with stable ischemic heart disease to insulin provision ( IP
Brown, David L +3 more
core +2 more sources