Results 11 to 20 of about 92,833 (358)

A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

Cell Reports, 2018
Summary: Fibroblast growth factor 21 (FGF21) is a hormone that has insulin-sensitizing properties. Some trials of FGF21 analogs show weight loss and lipid-lowering effects.
Timothy M. Frayling, Robin N. Beaumont, Samuel E. Jones, Hanieh Yaghootkar, Marcus A. Tuke, Katherine S. Ruth, Francesco Casanova, Ben West, Jonathan Locke, Seth Sharp, Yingjie Ji, William Thompson, Jamie Harrison, Amy S. Etheridge, Paul J. Gallins, Dereje Jima, Fred Wright, Yihui Zhou, Federico Innocenti, Cecilia M. Lindgren, Niels Grarup, Anna Murray, Rachel M. Freathy, Michael N. Weedon, Jessica Tyrrell, Andrew R. Wood   +25 more
doaj   +2 more sources

Insulin sensitizing drugs for weight loss in women of reproductive age who are overweight or obese: systematic review and meta-analysis.

Human Reproduction Update, 2008
A. E. Nieuwenhuis-Ruifrok, W. Kuchenbecker, A. Hoek, P. Middleton, R. Norman   +4 more
semanticscholar   +3 more sources

Photo-FETs: phototransistors enabled by 2D and 0D nanomaterials [PDF]

, 2016
The large diversity of applications in our daily lives that rely on photodetection technology requires photodetectors with distinct properties. The choice of an adequate photodetecting system depends on its application, where aspects such as spectral ...
Konstantatos, Gerasimos, Kufer, Dominik
core   +2 more sources

The sympathetic nervous system exacerbates carotid body sensitivity in hypertension

Cardiovascular Research, 2022
AbstractAimsThe carotid bodies (CBs) of spontaneously hypertensive (SH) rats exhibit hypertonicity and hyperreflexia contributing to heightened peripheral sympathetic outflow. We hypothesized that CB hyperexcitability is driven by its own sympathetic innervation.Methods and resultsTo test this, the chemoreflex was activated (NaCN 50–100 µL, 0.4 µg/µL ...
Igor S A Felippe, Tymoteusz Zera, Melina P da Silva, Davi J A Moraes, Fiona McBryde, Julian F R Paton   +5 more
openaire   +2 more sources

FGF21 Mediates the Thermogenic and Insulin-Sensitizing Effects of Dietary Methionine Restriction but Not Its Effects on Hepatic Lipid Metabolism

Diabetes, 2017
Dietary methionine restriction (MR) produces a rapid and persistent remodeling of white adipose tissue (WAT), an increase in energy expenditure (EE), and enhancement of insulin sensitivity.
D. Wanders, L. Forney, K. P. Stone, David Burk, Alicia Pierse, T. Gettys   +5 more
semanticscholar   +1 more source

Contact Dermatitis in Nail Cosmetics

Allergies, 2021
Many ingredients found within nail cosmetic products are capable of sensitizing patients’ immune systems and causing contact dermatitis (CD). These include but are not limited to tosylamide, (meth)acrylates, and formaldehyde.
Zoe M. Lipman, Antonella Tosti
doaj   +1 more source

Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine [PDF]

, 2014
Peer reviewedPublisher ...
Anne-Sophie eDelbes, Celine eCansell, Francois eTronche, Frederic eAmbroggi, Frederic eAmbroggi, Jacques eBARIK, Jacques eBARIK, Marc eTuriault, Marie-Louise eDongelmans, Pier Vincenzo Piazza, Sebastien eParnaudeau, Sebastien eParnaudeau, Serge H Luquet   +12 more
core   +6 more sources

Maternal obesity results in decreased syncytiotrophoblast synthesis of palmitoleic acid, a fatty acid with anti‐inflammatory and insulin‐sensitizing properties

The FASEB Journal, 2019
The fetus is dependent on delivery of fatty acids (FAs) by the syncytiotrophoblast, the transporting epithelium of the human placenta. Obese pregnant women have dyslipidemia; however, whether obesity impacts placental lipid transport and metabolism ...
V. Ferchaud-Roucher, Kelsey Barner, T. Jansson, T. Powell   +3 more
semanticscholar   +1 more source

Chloroquine plays a cell-dependent role in the response to treatment of pancreatic adenocarcinoma [PDF]

, 2018
In this study, our aim is to assess the role played by autophagy and its inhibition in the different PDAC cellular compartments, and its involvement in chemo-resistance using primary human pancreatic cancer-derived cells (PCC) and Cancer Associated ...
Bintz, Jennifer, Fanale, Daniele, Gayet, Odile, Iovanna, Juan Lucio, Molejon, Maria Ines, Soubeyran, Philippe, Swayden, Mirna   +6 more
core   +1 more source

The Naked Truth: The Face and Body Sensitive N170 Response Is Enhanced for Nude Bodies

PLoS ONE, 2011
Recent event-related potential studies have shown that the occipitotemporal N170 component--best known for its sensitivity to faces--is also sensitive to perception of human bodies. Considering that in the timescale of evolution clothing is a relatively new invention that hides the bodily features relevant for sexual selection and arousal, we ...
Hietanen, Jari K., Nummenmaa, Lauri
openaire   +7 more sources