Results 121 to 130 of about 3,457,736 (354)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Efficient Edge AI for Next Generation Smart Mirror Applications

open access: yesIEEE Access
A natural user interaction interface is required to enhance living environments to be fully smart, which would imply features like user-specific, individual interaction as well as awareness of context, situation, and environment.
Nils Kucza   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Tunable nanoplasmonic sensor based on the asymmetric degree of Fano resonance in MDM waveguide [PDF]

open access: gold, 2016
Shiping Zhan   +6 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Designing a New Dynamic Mechanical Analysis (DMA) System for Testing Viscoelastic Materials at High Frequencies

open access: yesModelling and Simulation in Engineering, 2019
The aim of this study is to design a new dynamic mechanical analysis (DMA) measurement system that can operate for shear tests at frequencies as high as 10 kHz with strain amplitudes sufficient for viscoelastic materials operating in high-frequency ...
Roja Esmaeeli   +4 more
doaj   +1 more source

Human activity monitoring system based on wearable sEMG and accelerometer wireless sensor nodes [PDF]

open access: gold, 2018
Giorgio Biagetti   +4 more
openalex   +1 more source

Biofunctionalization of Graphene‐Based FET Sensors through Heterobifunctional Nanoscaffolds: Technology Validation toward Rapid COVID‐19 Diagnostics and Monitoring

open access: green, 2022
Esteban Piccinini   +7 more
openalex   +2 more sources

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