Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Predicting Momentary Mood in Daily Life from Accelerometer Data: Evaluating Single vs. Multiple Sensor Locations Using Machine Learning. [PDF]
Woll S +5 more
europepmc +1 more source
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Interdigitated capacitive strain sensor enables precise yoga-inspired motion tracking. [PDF]
Papaefstathiou M, Elgendi M, Menon C.
europepmc +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Smartphone-Based Blood Pressure Monitoring via the Oscillometric Finger Pressing Method: Investigation of the DC Component of PPG. [PDF]
Freithaler M +7 more
europepmc +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Machine learning-based prediction of polyvinyl alcohol product viscosity and design of optimal process conditions. [PDF]
Nomura R +5 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Triboelectric Wearable Sensors for Human-Centric Smart Electronics: From Self-Powered Sensing to Artificial Intelligence-Assisted Human-Machine Interface Systems. [PDF]
Ra Y, Cho S, Guo X, Choi D, Lee C.
europepmc +1 more source

