Results 51 to 60 of about 26,151 (258)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Method for Localization Aerial Target in AC Electric Field Based on Sensor Circular Array

Sensors, 2020
The traditional method of using electric field sensors to realize early warning of electric power safety distance cannot measure the distance of dangerous sources. Therefore, aiming at the electric field with a frequency of 50 to 60 Hz (AC electric field)
Wenbin Zhang, Peng Li, Nianrong Zhou, Chunguang Suo, Weiren Chen, Yanyun Wang, Jiawen Zhao, Yincheng Li   +7 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Optimization of a Drone-Based System for Instrumental Odor Monitoring Using Feature Selection

Proceedings
The application of Instrumental Odor Monitoring Systems (IOMS) for odor concentration estimation in wastewater treatment plants remains a challenge. We present the optimization of a heterogeneous gas sensor array mounted on a small drone to be used in ...
Alessandro Benegiamo, Javier Burgués, Javier Alonso-Valdesueiro, Beatrice Julia Lotesoriere, Lara Terrén, Lidia Sauco, Mª Deseada Esclapez, Silvia Doñate, Agustín Gutiérrez-Gálvez, Santiago Marco   +9 more
doaj   +1 more source

Molecularly Imprinted Sol-Gel-Based QCM Sensor Arrays for the Detection and Recognition of Volatile Aldehydes

Sensors, 2017
The detection and recognition of metabolically derived aldehydes, which have been identified as important products of oxidative stress and biomarkers of cancers; are considered as an effective approach for early cancer detection as well as health status ...
Chuanjun Liu, Bartosz Wyszynski, Rui Yatabe, Kenshi Hayashi, Kiyoshi Toko   +4 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Enhanced Dipole Model-Based Magnetic Disturbance Compensation Using Magnetometer Arrays

Machines
Magnetometers are widely used in robotics and localization systems but are susceptible to magnetic disturbances generated by nearby ferromagnetic objects, which degrade their accuracy.
Massimo Stefanoni, Imre Kovács, Ákos Odry, Peter Sarcevic   +3 more
doaj   +1 more source

Odor Detection Using an E-Nose With a Reduced Sensor Array

Sensors, 2020
Recent advances in the field of electronic noses (e-noses) have led to new developments in both sensors and feature extraction as well as data processing techniques, providing an increased amount of information.
Piotr Borowik, Leszek Adamowicz, Rafał Tarakowski, Krzysztof Siwek, Tomasz Grzywacz   +4 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source