Results 51 to 60 of about 186,216 (345)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Improved Adaptive Hybrid Compensation for Compound Faults of Non-Gaussian Stochastic Systems

open access: yesIEEE Access, 2019
This study investigates an adaptive estimation and hybrid parallel distribution compensation for non-Gaussian stochastic systems with actuator-sensor compound faults.
Kaiyu Hu, Changyun Wen, Aili Yusup
doaj   +1 more source

Intermediate observer based simultaneous estimation of system states and multiple faults

open access: yesIET Control Theory & Applications, 2023
In this paper, an intermediate observer is proposed for simultaneously estimating the system state, actuator fault and sensor fault. The necessary and sufficient condition is given with respect to the existence of the designed observer. The observer gain
Jiantao Shi   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Robust air data sensor fault diagnosis with enhanced fault sensitivity using moving horizon estimation [PDF]

open access: yes2016 American Control Conference (ACC), 2016
This paper investigates robust fault diagnosis of multiple air data sensor faults in the presence of winds. The trade-off between robustness to winds and sensitivity to faults is challenging due to simultaneous influence of winds and latent faults on monitored sensors. Different from conventional residual generators that do not consider any constraints,
Wan, Yiming   +2 more
openaire   +2 more sources

Sensor fault estimation using LPV sliding mode observers with erroneous scheduling parameters

open access: yesat - Automatisierungstechnik, 2019
This paper proposes a linear parameter-varying sliding mode observer for the purpose of simultaneously estimating the system states and reconstructing sensor faults.
Lejun Chen, C. Edwards, H. Alwi
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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