Results 31 to 40 of about 80,379 (230)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

An adaptive envelope analysis in a wireless sensor network for bearing fault diagnosis using fast kurtogram algorithm [PDF]

open access: yes, 2014
This paper proposes a scheme to improve the performance of applying envelope analysis in a wireless sensor network for bearing fault diagnosis. The fast kurtogram is realized on the host computer for determining an optimum band-pass filter for the ...
Ball, Andrew   +5 more
core  

FAST : a fault detection and identification software tool [PDF]

open access: yes, 2016
The aim of this work is to improve the reliability and safety of complex critical control systems by contributing to the systematic application of fault diagnosis.
Duatis Juárez, Jordi
core   +4 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A distributed networked approach for fault detection of large-scale systems [PDF]

open access: yes, 2016
Networked systems present some key new challenges in the development of fault diagnosis architectures. This paper proposes a novel distributed networked fault detection methodology for large-scale interconnected systems.
Boem, F   +4 more
core   +1 more source

Surviving sensor network software faults [PDF]

open access: yesProceedings of the ACM SIGOPS 22nd symposium on Operating systems principles, 2009
We describe Neutron, a version of the TinyOS operating system that efficiently recovers from memory safety bugs. Where existing schemes reboot an entire node on an error, Neutron's compiler and runtime extensions divide programs into recovery units and reboot only the faulting unit. The TinyOS kernel itself is a recovery unit: a kernel safety violation
Yang Chen   +4 more
openaire   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

An active fault tolerant control approach to an offshore wind turbine model [PDF]

open access: yes, 2014
The paper proposes an observer based active fault tolerant control (AFTC) approach to a non-linear large rotor wind turbine benchmark model. A sensor fault hiding and actuator fault compensation strategy is adopted in the design.
Patton, Ron, Shi, Fengming
core   +1 more source

FULL VEHICLE ACTIVE SUSPENSION: SENSOR FAULT DIAGNOSIS AND FAULT TOLERANCE

open access: yesIFAC Proceedings Volumes, 2006
Abstract In this paper, sensor fault detection, identification and fault tolerance model-based approach is designed for a linear full vehicle's active suspension system. The approach uses a bank of reduced order sliding mode observers to generate residuals.
Abbas Chamseddine   +2 more
openaire   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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