Results 51 to 60 of about 80,379 (230)
A distributed fault-detection and diagnosis system using on-line parameter estimation [PDF]
The development of a model-based fault-detection and diagnosis system (FDD) is reviewed. The system can be used as an integral part of an intelligent control system.
Duyar, A., Guo, T.-H., Merrill, W.
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Decentralized fault-tolerant control of inland navigation networks: a challenge [PDF]
, 2016 Inland waterways are large-scale networks used principally for navigation. Even if the transport planning is an important issue, the water resource management is a crucial point.
Blesa Izquierdo, Joaquim +5 more
core
Sensor placement for fault location identification in water networks: A minimum test cover approach
, 2016 This paper focuses on the optimal sensor placement problem for the identification of pipe failure locations in large-scale urban water systems. The problem involves selecting the minimum number of sensors such that every pipe failure can be uniquely ...
Abbas, Waseem +3 more
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Sensor selection based on principal component analysis for fault detection in wind turbines [PDF]
, 2016 Growing interest for improving the reliability of safety-critical structures, such as wind turbines, has led to the advancement of structural health monitoring (SHM).
Pozo Montero, Francesc +1 more
core
System-level key performance indicators for building performance evaluation [PDF]
, 2020 Quantifying building energy performance through the development and use of key performance indicators (KPIs) is an essential step in achieving energy saving goals in both new and existing buildings. Current methods used to evaluate improvements, however,
Hong, T, Lee, SH, Li, H, Sofos, M
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source