Results 71 to 80 of about 354,199 (330)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A Comprehensive Review on Sensor Fusion Techniques for Localization of a Dynamic Target in GPS-Denied Environments

open access: yesIEEE Access
Although Global Navigation Satellite Systems (GNSS) typically provide sufficient accuracy for outdoor positioning, positioning systems face significant challenges in complex application scenarios, particularly in GPS-denied environments (GDE).
Shoude Wang, Nur Syazreen Ahmad
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A Review of Environmental Perception Technology Based on Multi-Sensor Information Fusion in Autonomous Driving

open access: yesWorld Electric Vehicle Journal
Environmental perception is a key technology for autonomous driving, enabling vehicles to analyze and interpret their surroundings in real time to ensure safe navigation and decision-making.
Boquan Yang, Jixiong Li, Ting Zeng
doaj   +1 more source

A Novel Data Fusion Strategy Based on Extreme Learning Machine Optimized by Bat Algorithm for Mobile Heterogeneous Wireless Sensor Networks

open access: yesIEEE Access, 2020
In order to effectively reduce the redundant information transmission in the network, a data fusion algorithm based on extreme learning machine optimized by bat algorithm for mobile heterogeneous wireless sensor networks is proposed.
Li Cao   +4 more
doaj   +1 more source

Robust Deep Multi-Modal Sensor Fusion using Fusion Weight Regularization and Target Learning

open access: yes, 2019
Sensor fusion has wide applications in many domains including health care and autonomous systems. While the advent of deep learning has enabled promising multi-modal fusion of high-level features and end-to-end sensor fusion solutions, existing deep ...
Li, Peng   +5 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Underwater Positioning Method Based on Vision-Inertia-Pressure Fusion

open access: yes水下无人系统学报
In underwater unstructured environments, robots face difficulties in relying on external base stations for localization. Therefore, autonomous localization using multi-sensor fusion has significant application value in such settings.
Jian ZHANG   +4 more
doaj   +1 more source

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