Results 61 to 70 of about 75,120 (301)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Pesquisa Agropecuária Brasileira, 2000 This paper describes a low-cost microprocessed instrument for in situ evaluating soil temperature profile ranging from -20.0°C to 99.9°C, and recording soil temperature data at eight depths from 2 to 128 cm.
PAULO ESTEVÃO CRUVINEL
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Avaliação de arquiteturas de comunicação distribuidas para interligação de sensores: atuadores em um helicoptero não tripulado [PDF]
, 1996 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnologico. Programa de Pós-Graduação em Engenharia EletricaA presente dissertação apresenta uma proposta de arquitetura de comunicação distribuída para a interligação de sensores ...
Correa, Ligia Cristina Fascioni
core
Evaluación del diseño de una pequeña mesa vibratoria para ensayos en ingeniería sismo-resistente
Ciencia e Ingeniería Neogranadina, 2013 Las consecuencias catastróficas de los sismos han incentivado la realización de estudios experimentales para mitigar los efectos de los sismos sobre las estructuras. En el artículo se presenta la evaluación de los diseños mecánico, neumático, estructural,
Julián Carrillo +2 more
doaj +1 more source
Tecnologías para la detección de ocupación en edificios
Prisma Tecnológico, 2020 Una importante parte del consumo de energía de los edificios está relacionado con el comportamiento de los ocupantes. Lo que significa que es necesario conocer con mayor precisión cómo se comporta y se mueve el usuario dentro de los ambientes, y este es ...
Dafni Mora +2 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
, 2014 El estudio y diseño de un sistema para realizar la medición remota para los servicios de energía eléctrica y agua potable, está enfocado a mejorar los métodos de trabajo tradicional en la toma de lecturas del consumo del servicio.
Urbina Gamboa, Wilmer Marcelo
core +1 more source