Results 131 to 140 of about 47,990 (266)

Beyond the nose: hearing status in 70 patients with congenital choanal atresia. [PDF]

open access: yesEur J Pediatr
Yılmaz Topçuoğlu MS   +3 more
europepmc   +1 more source

Inborn errors of immunity in children with neuroinflammation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu   +5 more
wiley   +1 more source

Glycemic and Renal Effects of SGLT2 Inhibitors in Monogenic Diabetes: A Real‐World National Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Evidence regarding the efficacy and safety of sodium–glucose cotransporter 2 inhibitors (SGLT2i) in monogenic diabetes is limited. We evaluated real‐world metabolic, renal, and safety outcomes of SGLT2i therapy in adults with monogenic diabetes.
Estelle Audrain   +15 more
wiley   +1 more source

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer   +3 more
wiley   +1 more source

Perioperative Transfusion Trigger Score Versus Restrictive Transfusion in Older Non‐Cardiac Surgery Patients: A Multicenter Randomized Controlled Trial

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang   +9 more
wiley   +1 more source

Hearing Aid Use Attenuates the Association Between Hearing Loss and Frailty: A 2003–2018 NHANES Cross Sectional Analysis

open access: yesJournal of the American Geriatrics Society, EarlyView.
Conceptual framework illustrating the hypothesized association between hearing loss and frailty, including the confounders and effect measure modifiers evaluated in this study. ABSTRACT Objective To examine the association between objectively measured hearing ability and frailty using the accumulation of deficits model in adults aged ≥ 65 years and ...
Cora Leigh White   +5 more
wiley   +1 more source

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