Results 271 to 280 of about 93,748 (336)

Conductive Materials and Electrical Stimulation for Auditory Restoration

open access: yesSensory Neuroscience, Volume 1, Issue 3, December 2025.
Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao   +8 more
wiley   +1 more source

PIK3C2A‐Related Clinical Phenotype and Cellular Charaterization Linked to Functional SHH Primary Cilia Defect

open access: yesClinical Genetics, Volume 108, Issue 6, Page 696-707, December 2025.
Trio exome sequencing allowed the identification of two novel compound heterozygous variants in PIK3C2A, defining the fifth family presenting a PIK3C2A‐related syndrome characterized by pulverulent cataracts and deafness. Functional testing revealed impaired PI metabolism and primary dysfunction phenotype.
Adella Karam   +9 more
wiley   +1 more source

The influence of targeted therapies in the inner ear. [PDF]

open access: yesFront Pharmacol
Bonilla T   +3 more
europepmc   +1 more source

Hearing Threshold Estimation With Distortion Product Otoacoustic Emission Growth Functions in People With Intellectual Disabilities in an Outreach Setting

open access: yesJournal of Intellectual Disability Research, Volume 69, Issue 12, Page 1474-1485, December 2025.
ABSTRACT Background People with intellectual disabilities often have undetected hearing loss. Methods In this prospective observational study featuring 110 adults with intellectual disabilities, hearing evaluations based on objective hearing threshold estimation using distortion‐product otoacoustic emission growth functions (DPOAEgfs) were performed in
Eleftherios Savvas   +9 more
wiley   +1 more source

Human Cytomegalovirus Associated Neuropathies: A Comprehensive Review From Pathophysiology to Clinical and Therapeutic Considerations

open access: yesJournal of the Peripheral Nervous System, Volume 30, Issue 4, December 2025.
ABSTRACT Human cytomegalovirus (HCMV) is a neurotropic, double‐stranded DNA virus from the Herpesviridae family. It has a large genome, infects the majority of populations, and typically causes asymptomatic infections in healthy individuals. After the initial infection with established lifelong latency, HCMV can reactivate and cause disorders including
Naomi Behanan   +4 more
wiley   +1 more source

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