Results 281 to 290 of about 87,827 (343)

Long‐Term Outcomes of Adult Temporal Bone Fractures With Hearing Loss: Results of a Multinational Database Analysis

open access: yesThe Laryngoscope, Volume 135, Issue 9, Page 3338-3347, September 2025.
This study uses a large multinational database to examine long‐term outcomes of adult temporal bone fractures. The risk for meningitis, labyrinthitis, facial nerve disorders, and cerebrospinal fluid leaks was elevated after fracture. Cochlear implantation was also more likely after temporal bone fracture.
Jason L. Steele   +7 more
wiley   +1 more source

Percutaneous Bone Implant Surgery: A MIPS Modified Technique

open access: yesThe Laryngoscope, Volume 135, Issue 9, Page 3378-3381, September 2025.
Since their introduction, passive percutaneous hearing aids have undergone substantial evolution, including changes in implant production, improvements in the sound processor, and simplification of surgical implantation techniques. The latest innovation comes from the minimally invasive technique proposed for the PONTO system (MIPS), which does not ...
Sofia Pizzolante   +3 more
wiley   +1 more source

Mitochondrial Diseases: Molecular Pathogenesis and Therapeutic Advances

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Key pathogenic mechanisms—OXPHOS defects, heteroplasmy, impaired mtDNA repair, disrupted dynamics/mitophagy, and inflammatory signaling—drive multiorgan involvement in mitochondrial diseases. Targeted interventions include metabolic drugs (CoQ10, idebenone, EPI‐743), mitochondrial gene editing (DdCBE, mitoBEs, CyDENT/mitoTALEN/mtZFN), and mitochondrial
Jialun Mei   +6 more
wiley   +1 more source

Clinical Characteristics and Identification of Pathogenic Variant in a Large Chinese Family With Waardenburg Syndrome

open access: yesMolecular Genetics &Genomic Medicine, Volume 13, Issue 9, September 2025.
We reported a 5‐generation family with autosomal dominant Waardenburg syndrome and identified a heterozygous variant of the SOX10 gene by exome sequencing and Sanger sequencing. In addition, we performed prenatal diagnosis for family related individual.
Fei Hou   +5 more
wiley   +1 more source

Patterns of Teprotumumab‐Induced Hearing Dysfunction: A Systematic Review

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 539-545, September 2025.
Abstract Objective Hearing loss has been reported after administration of the monoclonal antibody teprotumumab. The purpose of this study was to review available evidence regarding the patterns of teprotumumab‐related ototoxicity. Data Sources PubMed, EMBASE, and Cochrane Library.
Kevin Wong   +8 more
wiley   +1 more source

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