Results 61 to 70 of about 74,884 (346)

Characteristics of Mid-Frequency Sensorineural Hearing Loss Progression. [PDF]

, 2019
OBJECTIVES:To characterize the progression of mid-frequency sensorineural hearing loss (MFSNHL) over time. METHODS:A retrospective chart review spanning 2012 to 2017 was performed at a tertiary care audiology and neurotology center.
Abouzari, Mehdi, Birkenbeuel, Jack, Cheung, Dillon, Djalilian, Hamid R, Gelnett, Donna, Goshtasbi, Khodayar, Lin, Harrison W, Moshtaghi, Afsheen, Moshtaghi, Omid, Sahyouni, Ronald   +9 more
core   +2 more sources

A Recessive Mutation Resulting in a Disabling Amino Acid Substitution (T194R) in the LHX3 Homeodomain Causes Combined Pituitary Hormone Deficiency [PDF]

, 2012
Background/Aims: Recessive mutations in the LHX3 homeodomain transcription factor gene are associated with developmental disorders affecting the pituitary and nervous system. We describe pediatric patients with combined pituitary hormone deficiency (CPHD)
Bechtold-Dalla Pozza, Susanne, Duran-Prado, Mario, Hiedl, Stefan, Lohse, Peter, Malik, Raleigh E., Park, Soyoung, Rhodes, Simon J., Roeb, Julia   +7 more
core   +1 more source

Etiology of Sensorineural Deafness

Pediatric Neurology Briefs, 1996
Children with a bilateral sensorineural hearing impairment averaging 30 dBHL or or more were investigated for possible congenital or intrauterine infection as causes at the Centre for Audiology, Manchester University, UK.
openaire   +3 more sources

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Tuberculous Meningitis Presented with Bilateral Sensorineural Hearing Loss: Acute Deafness

Türk Nöroloji Dergisi, 2011
Tuberculous meningitis is the most severe manifestation of extrapulmonary tuberculosis with a high mortality and morbidity rates. It is usually presented with headache, fever, consciousness disturbances and convulsions. Eigth cranial nerve involvement is
Kürşad Çetin Akpınar, Hakan Doğru, Kemal Balcı   +2 more
doaj   +2 more sources

Intralabyrinthine Vestibular Schwannoma Responsive to Intratympanic Gentamicin Treatment [PDF]

, 2017
Intralabyrinthine schwannoma (ILS) is a rare benign tumor that affects the ends of cochlear and vestibular nerves. In a majority of the cases, it occurs with unilateral progressive sensorineural hearing loss.
Barbara, Maurizio, Covelli, Edoardo, Filippi, Chiara, Marrone, V, Monini, Simonetta, Tarentini, S, Volpini, Luigi   +6 more
core   +1 more source

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

Advanced Science, EarlyView.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang, Yongchuan Chai, Yiwen Zhang, Huan Jia, Zhaoyan Wang, Zhihua Zhang, Zhili Wang, Jie Chen, Xue Wang, Yun Li, Ying Chen, Hao Wu   +11 more
wiley   +1 more source

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

Advanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang, Li Zhang, Sen Chen, Le Xie, Yue Qiu, Chenyang Kong, Ge Yin, Weijia Kong, Yu Sun   +8 more
wiley   +1 more source

Kearns‐Sayre syndrome case. Novel 5,9 kb mtDNA deletion

Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
Novel 5,9 kb mtDNA deletion was identified for a 20‐year‐old male who presented with classic Kearns‐Sayre syndrome. Different molecular genetic methods were applied to identify the mitochondrial DNA deletion, but obtaining conflicting research results demonstrated the importance of choosing relevant molecular genetic methods. Abstract Background Kearns‐
Kristina Grigalionienė, Birutė Burnytė, Danutė Balkelienė, Laima Ambrozaitytė, Algirdas Utkus   +4 more
wiley   +1 more source

Can unilateral, progressive or sudden hearing loss be immune-mediated in origin? [PDF]

, 2017
OBJECTIVE: The aim of the present study was to demonstrate that the positivity of nonspecific immunological tests could be found not only in bilateral hearing loss but also in unilateral cases, either sudden or progressive. METHOD: An observational case
Atturo, Francesca, Bandiera, Giorgio, Barbara, Maurizio, Colangeli, R, Monini, Simonetta   +4 more
core   +1 more source