Results 61 to 70 of about 92,090 (322)

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim   +9 more
wiley   +1 more source

DPOAE in HIV infected adults [PDF]

open access: yes, 2008
HIV infection is associated with impairment of hearing function, at any stage of disease causing complication to the external, middle, inner ear and CNS.
Bhat, Jayashree S, Ranjan, Rajesh
core  

Intratympanic dexamethasone microcrystals/lidocaine‐loaded PLGA non‐spherical microparticles for local drug delivery to the inner ear

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Optimized lidocaine‐loaded PLGA non‐spherical particles (LPNMs) and dexamethasone microcrystals (DEX MCs) were prepared. They were then mixed in sodium hyaluronate solution to obtain a co‐delivery system, administrated in guinea pigs to evaluate the pharmacokinetics and biocompatibility of the system.
Dongcheng Wang   +7 more
wiley   +1 more source

Bone conductive implants in single sided deafness [PDF]

open access: yes, 2015
Conclusion: The Bone Conductive Implants (BCI) showed to partly restore some of the functions lost when the binaural hearing is missing, such as in the single-sided deafness (SSD) subjects.
ATTURO, FRANCESCA   +4 more
core   +1 more source

Cutting‐Edge Advancements in Physical Stimulation for Spiral Ganglion Neuron Protection and Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai   +7 more
wiley   +1 more source

Transient otoacustic emissions with tone pip in individuals with sensorineural hearing loss Emissões otoacústicas transitórias com estímulo tone pip em indivíduos portadores de perda auditiva neurossensorial

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
Otoacoustic Emissions are generated by the cochlea in response to sound stimuli. They can be generated by clicks or specific frequency stimuli, such as tone pips. This is a quick and objective test with several applications. OBJECTIVE: To investigate the
Thays Bueno Takeda, Daniela Gil
doaj   +1 more source

Antioxidants and Vasodilators for the Treatment of Noise-Induced Hearing Loss: Are They Really Effective?

open access: yesFrontiers in Cellular Neuroscience, 2020
We live in a world continuously immersed in noise, an environmental, recreational, and occupational factor present in almost every daily human activity. Exposure to high-level noise could affect the auditory function of individuals at any age, resulting ...
Juan Carlos Alvarado   +3 more
doaj   +1 more source

Sensorineural hearing loss and prematurity [PDF]

open access: yesArchives of Disease in Childhood - Fetal and Neonatal Edition, 2000
To elucidate clinical antecedents of sensorineural hearing loss (SNHL) in very preterm infants.Case-control study.Fifteen children < 33 weeks' gestation with significant SNHL born between 1 January 1990 and 31 December 1994, detected within 9 months of birth, and 30 matched control children.Perinatal variables in the two groups were compared using non ...
Linda P. Hunt   +2 more
openaire   +3 more sources

Statistical shape modeling of the human inner ear through micro‐computed tomography imaging

open access: yesThe Anatomical Record, EarlyView.
In this study, 54 cadaveric temporal bone specimens underwent high‐resolution micro‐CT imaging. Images were semi‐automatically segmented and converted to 3D surface mesh models for morphological measurement and analysis. Statistical shape models were created for the inner ear, cochlea, and vestibular system, as well as for sex‐ and side‐based subgroups.
Carmine Spedaliere   +8 more
wiley   +1 more source

Risk factors for sensorineural hearing loss in children

open access: yesPayesh, 2002
Objective: To determine Risk factors for sensorineural hearing loss in children. Material & methods: The association of selected  risk factors with sensorineural hearing loss was assessed in a case- control study of 396 children aged under 6 years from ...
Sadighi J, Majlesi F
doaj  

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