Results 61 to 70 of about 45,940 (218)

Rate of Hearing Loss in Platinum‐Naïve Patients Receiving Immune Checkpoint Inhibitors

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Hearing loss from immune checkpoint inhibitors (ICIs) has been documented in case reports and case series. We present the largest retrospective study investigating the rate of ICI‐related ototoxicity in a monitored cohort of platinum‐naïve patients. Study Design Retrospective cohort study. Setting Tertiary‐care center.
Kaitlyn A. Brooks, Christopher G. Gidley, Olivia Grimley, Catherine Wang, Shirin Jivani, Dianna Roberts, Aung Naing, Jack Phan, Katherine Hutcheson, Xin Wang, Paul W. Gidley, Marc‐Elie Nader   +11 more
wiley   +1 more source

Perioperative stroke and hyperhomocysteinemia: a possible pathogenic link [PDF]

Korean Journal of Anesthesiology, 2018
Maurizio Acampa, Pietro Enea Lazzerini, Giuseppe Martini   +2 more
doaj   +1 more source

Apple Hearing Test Feature for the AirPods Pro 2: Accuracy, Reliability, and Time‐Efficiency

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the accuracy, test‐retest reliability, and time‐efficiency of Apple's Hearing Test Feature (HTF) compared to reference standard pure‐tone audiometry (PTA). Study Design Cross‐sectional validation study. Setting Single‐center study at a university clinic. PTA was performed in a sound‐treated booth.
Megan Kruger, Vinaya Manchaiah, De Wet Swanepoel   +2 more
wiley   +1 more source

Migraine Features in Patients With Sudden Sensorineural Hearing Loss

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the prevalence of migraine features among patients with sudden sensorineural hearing loss (SSNHL) and evaluate potential clinical associations. Study Design Retrospective survey‐based study. Setting Single institution tertiary care center. Methods 168 adult patients with SSNHL were recruited.
Yalda Yazdani, Ella J. Lee, Amanda Francis, Saharnaz Nedjat, Mehdi Abouzari, Hamid R. Djalilian   +5 more
wiley   +1 more source

Clinical Genetic Testing for Hearing Loss: Implications for Genetic Counseling and Gene-Based Therapies

Biomedicines
Genetic factors contribute significantly to congenital hearing loss, with non-syndromic cases being more prevalent and genetically heterogeneous. Currently, 150 genes have been associated with non-syndromic hearing loss, and their identification has ...
Nam K. Lee, Kristin M. Uhler, Patricia J. Yoon, Regie Lyn P. Santos-Cortez   +3 more
doaj   +1 more source

Congenital Rubella and CNS Defects

Pediatric Neurology Briefs, 1987
The University Department of Pediatrics and Child Health, Leeds, and the Department of Microbiology, Hospital for Sick Children, London, collaborated in a study of the time relations between maternal rubella infection in pregnancy and the presence and ...
J Gordon Millichap
doaj   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Pathogenesis of Age‐Related Hearing Loss and Therapeutic Strategies

Sensory Neuroscience, EarlyView.
ABSTRACT Age‐related hearing loss (ARHL) is a degenerative disorder of the auditory system, characterized by bilateral symmetrical sensorineural hearing loss that occurs with aging. As a highly prevalent age‐related condition worldwide, ARHL significantly impairs both the quality of life and mental health of the elderly.
Yu Xiao, Jiaxin Liu, Xiaohan Zhang, Miao Chang, Cheng Cheng, Yunhao Wu, Xiaolong Fu   +6 more
wiley   +1 more source

Role of Hearing Loss Genes in the Sensory Epithelia Associated With Meniere Disease

Sensory Neuroscience, EarlyView.
ABSTRACT Meniere disease (MD) is an inner ear disorder characterized by episodic vertigo, tinnitus, fluctuating sensorineural hearing loss (SNHL), and aural fullness. Its hallmark pathological feature is endolymphatic hydrops. MD shows significant familial clustering in European and East Asian populations, supporting a strong genetic component in ...
Jose A. Lopez‐Escamez, Qiuyue Mao, Patricia Perez‐Carpena   +2 more
wiley   +1 more source

Perfil dos limiares audiométricos e curvas timpanométricas de idosos Profile of audiometric thresholds and tympanometric curve of elderly patients

Brazilian Journal of Otorhinolaryngology, 2010
OBJETIVO: Traçar o perfil audiológico dos idosos atendidos em uma clínica escola da cidade de Belo Horizonte. MÉTODOS: Foram analisados todos os prontuários de pacientes que realizaram avaliação audiológica no período de Abril de 2004 a Agosto de 2007 em
Tatiana Marques Guerra, Lucimar Pires Estevanovic, Marcela de Ávila Meira Cavalcante, Rafaela Carolina Lopez Silva, Izabel Cristina Campolina Miranda, Victor Gandra Quintas   +5 more
doaj   +1 more source